Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | CRHBP | P24387 | 1/20 | 0.57 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.57 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30385493 | 0.97 | PPID (0.66) | PPIDKMT2ACRHBPCRHR2CSNK1D | |
| SCHEMBL13054407 | 0.87 | PPID (0.61) | PPIDKMT2ACRHBPCRHR2CSNK1D | |
| SCHEMBL11433691 | 0.86 | CRHBP (0.61) | KMT2ACRHBPCRHR2HDAC6GAA | |
| SCHEMBL9367294 | 0.85 | KMT2A (0.59) | PPIDKMT2AALDH1A1NPC1 | |
| SCHEMBL8030811 | 0.84 | GAA (0.61) | PPIDKMT2ACRHBPCRHR2HDAC4 | |
| SCHEMBL8932406 | 0.84 | PPID (0.58) | PPIDKMT2AALDH1A1MEN1NPC1 | |
| SCHEMBL11511869 | 0.84 | PPID (0.58) | PPIDKMT2AALDH1A1MEN1NPC1 | |
| SCHEMBL1222683 | 0.83 | HDAC4 (0.55) | PPIDKMT2ACRHBPCRHR2HDAC4 | |
| SCHEMBL11165331 | 0.82 | CRHBP (0.65) | KMT2ACRHBPCRHR2HDAC6GAA | |
| SCHEMBL3665504 | 0.82 | PPID (0.62) | PPIDHDAC4HDAC6POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0797579-B1 | ERYTHROMYCIN A 9-0-OXIME DERIVATIVES ENDOWED WITH ANTIBIOTIC ACTIVITY | ZAMBON SPA (IT) | 2000-03-15 | — | — | EP | disclosed |
| CN-1046535-C | Erythromycin A 9-0-oxime derivatives endowed with antibiotic activity | ZAMBON SPA (IT) | 1999-11-17 | — | — | CN | disclosed |
| US-5847092-A | Erythromycin A 9-0 oxime derivatives endowed with antibiotic activity | ZAMBON GROUP S.P.A. (IT) | 1998-12-08 | — | — | US | disclosed |
| CN-1169727-A | Erythromycin A 9-0-oxime derivatives endowed with antibiotic activity | ZAMBON SPA (IT) | 1998-01-07 | — | — | CN | disclosed |