Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.56 |
| ▸ | LTA4H | P09960 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.54 |
| ▸ | PPID | Q08752 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.52 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.51 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30385493 | 0.88 | PPID (0.66) | KMT2AALDH1A1PPIDNPC1 | |
| SCHEMBL8019506 | 0.85 | PPID (0.62) | KMT2AALDH1A1PPIDNPC1 | |
| SCHEMBL1203178 | 0.85 | ALOX5 (0.67) | ALOX5ALDH1A1LMNANR1H4L3MBTL1 | |
| SCHEMBL1222607 | 0.84 | RAB9A (0.65) | KMT2AALDH1A1LMNANR1H4PPID | |
| SCHEMBL548 | 0.82 | LTA4H (0.64) | LTA4HALDH1A1LMNANR1H4PPID | |
| SCHEMBL1222683 | 0.81 | HDAC4 (0.55) | KMT2AALDH1A1LMNAPPIDHPGD | |
| SCHEMBL5955117 | 0.81 | ALDH1A1 (0.64) | KMT2ALTA4HALDH1A1LMNANR1H4 | |
| SCHEMBL20500011 | 0.80 | CHRM4 (0.60) | ALOX5LTA4HNPC1HPGDCHRM4 | |
| SCHEMBL8389369 | 0.80 | NPC1 (0.71) | KMT2AALOX5ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL26727982 | 0.80 | GSK3B (0.63) | KMT2AALDH1A1NR1H4PPIDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409163-B1 | Novel cyclic vinylogous N-hydroxy-N-methylureas useful as 5-lipoxygenase inhibitors | MERRELL DOW PHARMA (US) | 1994-12-21 | — | — | EP | disclosed |