Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18383081 | 0.94 | LTA4H (0.50) | ESR2ALOX5MAPK1RAB9AALDH1A1 | |
| SCHEMBL343939 | 0.93 | CA1 (0.55) | MAPK1RAB9AALDH1A1TSHRTDP1 | |
| SCHEMBL3071819 | 0.93 | CA1 (0.55) | MAPK1RAB9AALDH1A1TSHRTDP1 | |
| SCHEMBL931283 | 0.93 | CA1 (0.55) | MAPK1RAB9AALDH1A1TSHRTDP1 | |
| SCHEMBL29510642 | 0.91 | CA1 (0.52) | MAPK1RAB9AALDH1A1TSHRTDP1 | |
| SCHEMBL18383080 | 0.87 | LTA4H (0.56) | MAPK1RAB9AALDH1A1TSHRTDP1 | |
| SCHEMBL13486840 | 0.85 | CYP11B1 (0.60) | ESR2ALOX5MAPK1RAB9ATSHR | |
| SCHEMBL28774522 | 0.85 | CA1 (0.46) | MAPK1RAB9AALDH1A1TSHRTDP1 | |
| Sulfuric Acid SCHEMBL22498737 | 0.83 | CA1 (0.51) | ALOX5MAPK1RAB9AALDH1A1TSHR | |
| SCHEMBL29861308 | 0.83 | PTPN5 (0.53) | ESR2ALDH1A1CYP11B1CYP11B2CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-63107946-A | — | — | None | — | — | JP | disclosed |
| WO-2009071504-A1 | 2,6-DISUBSTITUTED PYRIDINES AS SOLUBLE GUANYLATE CYCLASE ACTIVATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-06-11 | — | — | WO | disclosed |
| US-5447659-A | Hydrolysis of the ester derivative with esterase to form the alcohol | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-09-05 | — | — | US | disclosed |
| US-5338484-A | Optically active benzene derivatives, process for producing the same and liquid-crystalline substances containing said derivatives as active ingredient and optical switching elements | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-08-16 | — | — | US | disclosed |
| US-5274168-A | Optically active benzene derivatives, process for producing the same and liquid-crystalline substances containing said derivatives as active ingredient and optical switching elements | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-12-28 | — | — | US | disclosed |
| EP-0284371-B1 | NOVEL OPTICALLY ACTIVE BENZENE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND LIQUID-CRYSTALLINE SUBSTANCES CONTAINING SAID DERIVATIVES AS ACTIVE INGREDIENT AND OPTICAL SWITCHING ELEMENTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-09-16 | — | — | EP | disclosed |
| US-5002693-A | Novel optically active benzene derivatives, process for producing the same and liquid-crystalline substances containing said derivatives as active ingredient and optical switching elements | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-03-26 | — | — | US | disclosed |
| JP-S63107946-A | OPTICALLY ACTIVE BIPHENYL DERIVATIVE AND PRODUCTION THEREOF | SUMITOMO CHEM CO LTD | 1988-05-12 | — | — | JP | disclosed |
| US-4191776-A | ANTITHROMBOTICS, ANTICHOLESTEREMICS, ANTICOAGULANTS | BOEHRINGER INGELHEIM GMBH (DE) | 1980-03-04 | — | — | US | disclosed |
| US-3993683-A | ANTITHROMBOTIC, ANTICHOLESTEREMICS, ANTICOAGULANTS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-11-23 | — | — | US | disclosed |