SCHEMBL343939

SCHEMBL343939

COc1ccc([C@@H](C)O)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.55
CA2 P00918 2/20 0.55
CA12 O43570 1/20 0.55
CA7 P43166 1/20 0.55
CA9 Q16790 1/20 0.55
CA14 Q9ULX7 1/20 0.55
AOC3 Q16853 2/20 0.52
ALDH1A1 P00352 1/20 0.50
TSHR P16473 1/20 0.50
MAPK1 P28482 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
MEN1 O00255 1/20 0.48
RAB9A P51151 1/20 0.48
KMT2A Q03164 1/20 0.48
ACP3 P15309 1/20 0.47
SLC2A1 P11166 1/20 0.47
ACHE P22303 2/20 0.46
ABCB11 O95342 1/20 0.46
CYP1A2 P05177 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL931283 1.00 CA1 (0.55) CA1CA2CA12CA7CA9
SCHEMBL3071819 1.00 CA1 (0.55) CA1CA2CA12CA7CA9
SCHEMBL29510642 0.98 CA1 (0.52) CA1CA2CA12CA7CA9
SCHEMBL8019588 0.93 ESR2 (0.56) CA1CA2CA12CA7CA9
SCHEMBL18383080 0.93 LTA4H (0.56) CA1CA2CA12CA7CA9
SCHEMBL28774522 0.91 CA1 (0.46) CA1CA2CA12CA7CA9
Sulfuric Acid SCHEMBL22498737 0.89 CA1 (0.51) CA1CA2CA12CA7CA9
SCHEMBL18383082 0.88 LTA4H (0.50) CA1CA2CA12CA7CA9
SCHEMBL18383081 0.88 LTA4H (0.50) CA1CA2CA12CA7CA9
SCHEMBL18383076 0.88 LTA4H (0.50) CA1CA2CA12CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113862253-B Preparation method of composite carrier, composite carrier and resolution method of racemate by composite carrier 湖南理工学院 2024-08-09 CN claimed
CN-114405437-B Photoelectrocatalysis device and application thereof 太原师范学院 2023-10-27 CN claimed
CN-114405437-A Photoelectrocatalysis device and application thereof 太原师范学院 2022-04-29 CN claimed
CN-120082607-A Method for splitting chiral acid/alcohol through enzymatic esterification-hydrolysis cascade 华南理工大学 2025-06-03 CN disclosed
CN-118652881-A SOM-ZIF-8-PEG carrier immobilized enzyme and preparation method and application thereof 湖南理工学院 2024-09-17 CN disclosed
CN-113862253-B Preparation method of composite carrier, composite carrier and resolution method of racemate by composite carrier 湖南理工学院 2024-08-09 CN disclosed
CN-113862117-B Device and method for separating chiral substances by multi-liquid-phase system continuous enzyme method 华南理工大学 2024-03-12 CN disclosed
CN-114405437-B Photoelectrocatalysis device and application thereof 太原师范学院 2023-10-27 CN disclosed
CN-116904524-A Method for enzyme-catalyzed hydrolysis of ester substances by microfluidic three-liquid phase system 华南理工大学 2023-10-20 CN disclosed
EP-4257593-A1 CHIRAL MULTIDENTATE LIGAND AND USE THEREOF IN ASYMMETRIC HYDROGENATION SHENZHEN CATALYS TECHNOLOGY CO., LTD. (CN) 2023-10-11 EP disclosed
US-20230285945-A1 CATALYST CONTAINING ACTIVATED CARBON ADSORBED WITH RUTHENIUM COMPLEX, AND METHOD FOR PRODUCING REDUCTION PRODUCT USING SAME TAKASAGO INTERNATIONAL CORPORATION (JP) 2023-09-14 US disclosed
WO-2010141768-A2 POLYCYCLIC ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS AMIRA PHARMACEUTICALS, INC. (US) 2010-12-09 WO disclosed
WO-2010141768-A2 POLYCYCLIC ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS AMIRA PHARMACEUTICALS, INC. (US) 2010-12-09 WO disclosed
US-20100298179-A1 Mating member and a sliding member OILES CORPORATION (JP) 2010-11-25 US disclosed
US-20090253919-A1 Chiral thiourea compounds and process for enantioselective reduction of ketones BOARD OF REGENTS (US) 2009-10-08 US disclosed
EP-0978567-B1 PROCESS FOR PRODUCING OPTICALLY ACTIVE ALCOHOLS SANYO SHOKUHIN KK (JP) 2005-03-09 EP disclosed
US-20030171544-A1 Alcohol dehydrogenase and use thereof DEGUSSA AG (DE) 2003-09-11 US disclosed
EP-1241263-A1 Alcohol dehydrogenase and uses therefor Degussa AG (DE) 2002-09-18 EP disclosed
US-6218581-B1 SOLVENT EXTRACTION OF WATER SOLUBLE PROTEIN FROM BEAN OR GRAIN; ISOLATION, PURIFICATION OF ACYLATED FORM; HYDROLYSIS SANYO SHOKUHIN CO., LTD. (JP) 2001-04-17 US disclosed
EP-0978567-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE ALCOHOLS SANYO SHOKUHIN CO., LTD. (JP) 2000-02-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030171544-A1 Alcohol dehydrogenase and use thereof ADH5, ADH1A, ADH1C CA1 3221/4885CA2 3088/4885CA12 1467/4885
US-20230285945-A1 CATALYST CONTAINING ACTIVATED CARBON ADSORBED WITH RUTHENIUM COMPLEX, AND METHOD FOR PRODUCING REDUCTION PRODUCT USING SAME RRS1, POR, SCO2 CA1 400/4885CA2 244/4885CA12 886/4885
US-20090253919-A1 Chiral thiourea compounds and process for enantioselective reduction of ketones TREH, ADH1A, ADH1C CA1 1415/4885CA2 2153/4885CA12 1357/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.