Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7663243 | 0.89 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1MAPK1LMNAMAPT | |
| SCHEMBL7663344 | 0.89 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1MAPK1LMNAMAPT | |
| SCHEMBL7676271 | 0.86 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1MAPK1LMNAMAPT | |
| SCHEMBL8018821 | 0.84 | MAPT (0.61) | SMN1; SMN2ALDH1A1MAPK1LMNAMAPT | |
| SCHEMBL7662978 | 0.80 | SMN1; SMN2 (0.72) | SMN1; SMN2ALDH1A1MAPTKMT2AL3MBTL1 | |
| SCHEMBL15754508 | 0.80 | SMN1; SMN2 (0.72) | SMN1; SMN2ALDH1A1MAPK1MAPTKMT2A | |
| SCHEMBL8023083 | 0.78 | RAB9A (0.56) | SMN1; SMN2ALDH1A1MAPK1LMNAMAPT | |
| SCHEMBL8019190 | 0.78 | RAB9A (0.66) | SMN1; SMN2ALDH1A1MAPK1LMNAMAPT | |
| SCHEMBL22516213 | 0.77 | CYP2D6 (0.58) | SMN1; SMN2ALDH1A1MAPK1LMNAMAPT | |
| SCHEMBL8008535 | 0.77 | RAB9A (0.65) | SMN1; SMN2ALDH1A1MAPK1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000058277-A1 | ARYL SULFONIC ACIDS AND DERIVATIVES AS FSH ANTAGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-10-05 | — | — | WO | disclosed |