Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.72 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | PKM | P14618 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15765534 | 0.94 | SMN1; SMN2 (0.63) | SMN1; SMN2MAPTPKMPOLBALDH1A1 | |
| SCHEMBL15754508 | 0.92 | SMN1; SMN2 (0.72) | SMN1; SMN2MAPTPKMALDH1A1KMT2A | |
| SCHEMBL20240486 | 0.82 | SMN1; SMN2 (0.73) | SMN1; SMN2MAPTPKMALDH1A1KMT2A | |
| SCHEMBL7676271 | 0.82 | SMN1; SMN2 (0.58) | SMN1; SMN2MAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL4616589 | 0.81 | SMN1; SMN2 (0.69) | SMN1; SMN2PKMPOLBALDH1A1KMT2A | |
| SCHEMBL8073771 | 0.81 | KMT2A (0.58) | SMN1; SMN2PKMPOLBALDH1A1KMT2A | |
| SCHEMBL18830935 | 0.80 | CYP2C9 (0.56) | SMN1; SMN2MAPTPOLBALDH1A1KDM4E | |
| SCHEMBL20240439 | 0.80 | SMN1; SMN2 (0.75) | SMN1; SMN2PKMALDH1A1KMT2ATSHR | |
| SCHEMBL8019642 | 0.80 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTALDH1A1KDM4EKMT2A | |
| SCHEMBL7663344 | 0.80 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110698459-B | 1-phenyl-2-pyridylalkyl alcohol derivatives as phosphodiesterase inhibitors | 奇斯药制品公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-110698459-A | 1-phenyl-2-pyridylalkyl alcohol derivatives as phosphodiesterase inhibitors | 奇斯药制品公司 | 2020-01-17 | — | — | CN | disclosed |
| US-9944612-B2 | 1-phenyl-2-pyridinyl alkyl alcohol derivatives as phosphodiesterase inhibitors | CHIESI FARMACEUTICI S.P.A. (IT) | 2018-04-17 | — | — | US | disclosed |
| US-9944612-B2 | 1-phenyl-2-pyridinyl alkyl alcohol derivatives as phosphodiesterase inhibitors | CHIESI FARMACEUTICI S.P.A. (IT) | 2018-04-17 | — | — | US | disclosed |
| US-9944612-B2 | 1-phenyl-2-pyridinyl alkyl alcohol derivatives as phosphodiesterase inhibitors | CHIESI FARMACEUTICI S.P.A. (IT) | 2018-04-17 | — | — | US | disclosed |
| EP-2928869-A1 | 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOL DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2015-10-14 | — | — | EP | disclosed |
| WO-2014086865-A1 | 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOL DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2014-06-12 | — | — | WO | disclosed |
| WO-2014086865-A1 | 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOL DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2014-06-12 | — | — | WO | disclosed |
| US-20140155391-A1 | 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOL DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2014-06-05 | — | — | US | disclosed |
| US-20140155391-A1 | 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOL DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2014-06-05 | — | — | US | disclosed |
| US-20140155391-A1 | 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOL DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2014-06-05 | — | — | US | disclosed |
| US-20020111369-A1 | Aryl sulfonic acids and derivatives as FSH antagonists | AMERICAN HOME PRODUCTS CORPORATION (US) | 2002-08-15 | — | — | US | disclosed |
| US-6355633-B1 | CONTRACEPTIVES | AMERICAN HOME PRODUCTS CORPORATION | 2002-03-12 | — | — | US | disclosed |
| WO-2000058277-A1 | ARYL SULFONIC ACIDS AND DERIVATIVES AS FSH ANTAGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140155391-A1 | 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOL DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | PDE4A, PDE4B, PDE3A | SMN1; SMN2 2901/4885MAPT 4037/4885PKM 1567/4885 |
| US-20020111369-A1 | Aryl sulfonic acids and derivatives as FSH antagonists | FSHR, GNRHR, LHCGR | SMN1; SMN2 2927/4885MAPT 4858/4885PKM 4553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.