⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12595856 | 0.76 | ALDH1A1 (0.35) | — | |
| SCHEMBL4650659 | 0.75 | — | — | |
| SCHEMBL27656652 | 0.73 | ALDH1A1 (0.33) | — | |
| SCHEMBL22374011 | 0.73 | — | — | |
| SCHEMBL633600 | 0.71 | — | — | |
| SCHEMBL24496282 | 0.69 | — | — | |
| SCHEMBL17927777 | 0.69 | — | — | |
| SCHEMBL5663944 | 0.69 | — | — | |
| SCHEMBL10448024 | 0.69 | — | — | |
| SCHEMBL11130306 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10696711-B2 | Asymmetric auxiliary group | WAVE LIFE SCIENCES LTD. (SG) | 2020-06-30 | — | — | US | disclosed |
| US-20190177357-A1 | ASYMMETRIC AUXILIARY GROUP | WAVE LIFE SCIENCES JAPAN (JP) | 2019-06-13 | — | — | US | disclosed |
| EP-0617325-B1 | Method of processing originating photographic elements containing tabular silver chloride grains bounded by (100) faces | EASTMAN KODAK CO (US) | 2000-01-19 | — | — | EP | disclosed |
| US-5618656-A | DEVELOPING AND DESILVERING ORIGINATING ELEMENT AND DISPLAY ELEMENT USING SIMILAR PROCESSING SOLUTIONS, PROVIDED THAT SPECIFIED SILVER HALIDE EMULSION IS USED | EASTMAN KODAK COMPANY (US) | 1997-04-08 | — | — | US | disclosed |
| US-5443943-A | Method of processing originating photographic elements containing tabular silver chloride grains bounded by {100} faces | EASTMAN KODAK COMPANY (US) | 1995-08-22 | — | — | US | disclosed |
| EP-0617325-A1 | Method of processing originating photographic elements containing tabular silver chloride grains bounded by (100) faces | EASTMAN KODAK COMPANY (US) | 1994-09-28 | — | — | EP | disclosed |
| US-4529813-A | Preparation of 2-halogeno-3-alkylvinylcyclobutan-1-one | BAYER AKTIENGESELLSCHAFT (DE) | 1985-07-16 | — | — | US | disclosed |
| US-4291176-A | Production of insecticidally active vinyl-cyclopropane carboxylic acid esters | BAYER AKTIENGESELLSCHAFT (DE) | 1981-09-22 | — | — | US | disclosed |
| US-4216172-A | Preparation of cyclobutanones | BAYER AKTIENGESELLSCHAFT (DE) | 1980-08-05 | — | — | US | disclosed |