⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26675695 | 0.73 | — | — | |
| SCHEMBL9269457 | 0.69 | — | — | |
| SCHEMBL18888037 | 0.69 | — | — | |
| SCHEMBL8020065 | 0.69 | — | — | |
| SCHEMBL21992905 | 0.68 | TAS1R3 (0.37) | — | |
| SCHEMBL27656652 | 0.67 | ALDH1A1 (0.33) | — | |
| Sulfuric Acid SCHEMBL28181523 | 0.65 | — | — | |
| Sulfuric Acid SCHEMBL7934252 | 0.65 | ALDH1A1 (0.67) | — | |
| SCHEMBL633600 | 0.65 | — | — | |
| SCHEMBL24397665 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022120355-A1 | TEAD DEGRADERS AND USES THEREOF | Ikena Oncology, Inc. (US) | 2022-06-09 | — | — | WO | disclosed |
| WO-2022120353-A1 | TEAD INHIBITORS AND USES THEREOF | Ikena Oncology, Inc. (US) | 2022-06-09 | — | — | WO | disclosed |