Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.61 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.61 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.61 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.61 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8035817 | 0.83 | AIMP2 (0.54) | SIGMAR1AIMP2KMT2ATSHRMEN1 | |
| SCHEMBL18171334 | 0.81 | AIMP2 (0.81) | HTR1ASIGMAR1AIMP2KMT2ATSHR | |
| Hydrochloric Acid SCHEMBL18171335 | 0.80 | AIMP2 (0.80) | HTR1ASIGMAR1AIMP2KMT2ATSHR | |
| SCHEMBL13718018 | 0.79 | HPGD (0.56) | SIGMAR1KMT2ATSHRHPGDALDH1A1 | |
| SCHEMBL8029610 | 0.77 | AIMP2 (0.53) | SIGMAR1AIMP2KMT2ATSHRMEN1 | |
| SCHEMBL8031431 | 0.76 | SIGMAR1 (1.00) | HTR1AADRA2AADRA2BADRA2CSIGMAR1 | |
| SCHEMBL31061719 | 0.76 | SIGMAR1 (1.00) | HTR1AADRA2AADRA2BADRA2CSIGMAR1 | |
| SCHEMBL5080239 | 0.75 | KMT2A (0.78) | KMT2ATSHRMEN1ALDH1A1MAPK1 | |
| SCHEMBL11631159 | 0.74 | TSHR (0.72) | KMT2ATSHRMEN1ALDH1A1MAPT | |
| SCHEMBL3355843 | 0.73 | CYP1A2 (0.53) | AIMP2KMT2ATSHRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702010-B1 | Benzopyranderivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-03-15 | — | — | EP | disclosed |
| US-5691340-A | CENTRAL NERVOUS SYSTEM DISORDERS, STROKES, CARDIOVASCULAR DISORDERS, ALZHEIMER*S DISEASE OR ANTIINFLAMMATORY AGENTS | ADIR ET COMPAGNIE (FR) | 1997-11-25 | — | — | US | disclosed |
| US-5668138-A | AFFINITY FOR SIGMA RECEPTORS, CENTRAL NERVOUS SYSTEM DISORDERS | ADIR ET COMPAGNIE (FR) | 1997-09-16 | — | — | US | disclosed |
| EP-0702010-A1 | Benzopyranderivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-03-20 | — | — | EP | disclosed |