Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AIMP2 | Q13155 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | EEF2K | O00418 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15724690 | 0.81 | HPGD (0.51) | KMT2ATSHRHPGDMEN1 | |
| SCHEMBL20274120 | 0.81 | TSHR (0.48) | KMT2ATSHRHPGD | |
| SCHEMBL8020106 | 0.78 | SIGMAR1 (0.59) | SIGMAR1 | |
| SCHEMBL15707933 | 0.78 | HPGD (0.50) | TSHRHPGDALDH1A1 | |
| SCHEMBL8020110 | 0.77 | HTR1A (0.61) | AIMP2KMT2ATSHRHPGDALDH1A1 | |
| SCHEMBL15707945 | 0.76 | HPGD (0.45) | KMT2ATSHRHPGDMEN1 | |
| SCHEMBL3355450 | 0.76 | KMT2A (0.73) | AIMP2KMT2ATSHRHPGDALDH1A1 | |
| SCHEMBL18171334 | 0.75 | AIMP2 (0.81) | AIMP2KMT2ATSHRHPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL18171335 | 0.74 | AIMP2 (0.80) | AIMP2KMT2ATSHRHPGDALDH1A1 | |
| SCHEMBL8035817 | 0.73 | AIMP2 (0.54) | AIMP2KMT2ATSHRALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702010-B1 | Benzopyranderivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-03-15 | — | — | EP | disclosed |
| US-5691340-A | CENTRAL NERVOUS SYSTEM DISORDERS, STROKES, CARDIOVASCULAR DISORDERS, ALZHEIMER*S DISEASE OR ANTIINFLAMMATORY AGENTS | ADIR ET COMPAGNIE (FR) | 1997-11-25 | — | — | US | disclosed |
| US-5668138-A | AFFINITY FOR SIGMA RECEPTORS, CENTRAL NERVOUS SYSTEM DISORDERS | ADIR ET COMPAGNIE (FR) | 1997-09-16 | — | — | US | disclosed |
| EP-0702010-A1 | Benzopyranderivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-03-20 | — | — | EP | disclosed |