SCHEMBL8020141

SCHEMBL8020141

NC(=O)NCCO.[CaH2]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27663 0.97
SCHEMBL1228640 0.97 ALDH1A1 (0.48)
SCHEMBL28064222 0.94
SCHEMBL32684120 0.94
Oxalic Acid SCHEMBL29215671 0.89 ALDH1A1 (0.42)
Monoethanolamine SCHEMBL6872043 0.89 ALDH1A1 (0.42)
Glycerin SCHEMBL19206969 0.83 ALDH1A1 (0.48)
SCHEMBL30816421 0.81 ALDH1A1 (0.36)
Acrylic Acid SCHEMBL28515781 0.81 LMNA (0.43)
SCHEMBL175234 0.81 TDP1 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6120806-A Oral formulations for controlled release of alcohol deterrents WHITMIRE DAVID R (US) 2000-09-19 US disclosed
WO-1998058642-A1 ORAL FORMULATIONS FOR CONTROLLED RELEASE OF ALCOHOL DETERRENTS WHITMIRE DAVID R (US) 1998-12-30 WO disclosed
US-4940816-A Acylated cyanamide compounds REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1990-07-10 US disclosed
EP-0253882-A4 ACYLATED CYANAMIDE COMPOSITION. UNIV MINNESOTA (US) 1990-06-27 EP disclosed
US-4870056-A DETERRENTS OF ALCOHOL ABUSE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1989-09-26 US disclosed
US-4726941-A Acylated cyanamide composition for treating ethanol ingestion REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1988-02-23 US disclosed
EP-0253882-A1 ACYLATED CYANAMIDE COMPOSITION THE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1988-01-27 EP disclosed
WO-1987004348-A1 ACYLATED CYANAMIDE COMPOSITION REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1987-07-30 WO disclosed