Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9609808 | 0.85 | SMN1; SMN2 (0.82) | SMN1; SMN2HPGDMAPTRAB9ANPC1 | |
| SCHEMBL2088691 | 0.82 | PGR (0.62) | SMN1; SMN2HPGDMAPTRAB9ANPC1 | |
| SCHEMBL5528365 | 0.82 | PTPN11 (0.52) | SMN1; SMN2HPGDRAB9AALDH1A1CYP2C19 | |
| SCHEMBL599684 | 0.79 | KMT2A (0.73) | SMN1; SMN2HPGDMAPTRAB9ANPC1 | |
| SCHEMBL7251623 | 0.79 | SMN1; SMN2 (0.72) | SMN1; SMN2HPGDMAPTRAB9ANPC1 | |
| SCHEMBL2323162 | 0.78 | SMN1; SMN2 (0.57) | SMN1; SMN2HPGDMAPTRAB9ANPC1 | |
| SCHEMBL18814226 | 0.77 | SMN1; SMN2 (1.00) | SMN1; SMN2HPGDMAPTRAB9ANPC1 | |
| SCHEMBL9089994 | 0.77 | SMN1; SMN2 (0.69) | SMN1; SMN2HPGDMAPTRAB9ANPC1 | |
| SCHEMBL514571 | 0.77 | SMN1; SMN2 (0.69) | SMN1; SMN2HPGDMAPTRAB9ANPC1 | |
| SCHEMBL17518815 | 0.77 | SMN1; SMN2 (0.69) | SMN1; SMN2HPGDMAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675133-B1 | 13-Substituted milbemycin derivatives, their preparation and use | SANKYO CO (JP) | 2000-01-12 | — | — | EP | disclosed |
| US-5614470-A | AGRICULTURAL ANTHELMINTIC, ACARICIDE, INSECTICIDE | SANKYO COMPANY, LIMITED (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0675133-A1 | 13-Substituted milbemycin derivatives, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1995-10-04 | — | — | EP | disclosed |