Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.39 |
| ▸ | ESR1 | P03372 | 5/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8490628 | 0.88 | PRCP (0.46) | IRAK4ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL8490623 | 0.88 | PRCP (0.46) | IRAK4ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL8486785 | 0.81 | BTK (0.42) | IRAK4 | |
| SCHEMBL8487365 | 0.81 | BTK (0.42) | IRAK4 | |
| SCHEMBL8021939 | 0.79 | DRD2 (0.42) | IRAK4EML4ALKPRCPCNR1 | |
| SCHEMBL8483437 | 0.79 | BTK (0.43) | IRAK4CYP3A4CYP2C9 | |
| SCHEMBL8483434 | 0.79 | BTK (0.43) | IRAK4CYP3A4CYP2C9 | |
| SCHEMBL8490025 | 0.78 | IRAK4 (0.45) | IRAK4CYP3A4CYP2C9 | |
| SCHEMBL8582006 | 0.77 | IRAK4 (0.38) | IRAK4CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL8581999 | 0.77 | IRAK4 (0.38) | IRAK4CYP3A4CYP2C9CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6107299-A | INSECTICIDES; MITICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 2000-08-22 | — | — | US | disclosed |
| WO-1999059979-A1 | SUBSTITUTED PYRIDINE AND PYRIMIDINES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES | AVENTIS CROPSCIENCE GMBH (DE) | 1999-11-25 | — | — | WO | disclosed |