Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9131882 | 0.94 | KMT2A (0.47) | KMT2APKMHTTUSP2NPC1 | |
| SCHEMBL8031875 | 0.93 | MAPK1 (0.40) | KMT2AHTTMEN1PPARDLMNA | |
| SCHEMBL8020965 | 0.92 | KMT2A (0.48) | KMT2APKMHTTUSP2NPC1 | |
| SCHEMBL8020648 | 0.92 | KDM4E (0.38) | KMT2AHTTNPC1MEN1ALDH1A1 | |
| SCHEMBL8029961 | 0.92 | KMT2A (0.38) | KMT2APKMHTTUSP2NPC1 | |
| SCHEMBL8031868 | 0.91 | PPIB (0.38) | KMT2AHTTNPC1MEN1PPARD | |
| SCHEMBL8020901 | 0.91 | SMN1; SMN2 (0.37) | KMT2AHTTNPC1MEN1KDM4E | |
| SCHEMBL8033859 | 0.91 | SMN1; SMN2 (0.44) | KMT2APKMHTTNPC1MEN1 | |
| SCHEMBL8030246 | 0.91 | KMT2A (0.42) | KMT2APKMHTTUSP2NPC1 | |
| SCHEMBL8020574 | 0.91 | PTGDR2 (0.38) | KMT2AHTTNPC1MEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985660-A1 | AMINOPHENOL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-03-15 | — | — | EP | disclosed |