Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PPIB | P23284 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8031868 | 0.92 | PPIB (0.38) | PDE5ASMN1; SMN2MAPK1PPIBNPC1 | |
| SCHEMBL27487343 | 0.91 | ITGB1 (0.34) | SMN1; SMN2MAPK1PPIBNPC1RAB9A | |
| SCHEMBL8020628 | 0.91 | KMT2A (0.42) | SMN1; SMN2NPC1HTTMEN1KMT2A | |
| SCHEMBL8020901 | 0.90 | SMN1; SMN2 (0.37) | PDE5ASMN1; SMN2MAPK1PPIBNPC1 | |
| SCHEMBL8031875 | 0.90 | MAPK1 (0.40) | PDE5ASMN1; SMN2MAPK1HTTMEN1 | |
| SCHEMBL8020648 | 0.89 | KDM4E (0.38) | PDE5ASMN1; SMN2MAPK1PPIBNPC1 | |
| SCHEMBL8020736 | 0.89 | ITGB1 (0.36) | PDE5ASMN1; SMN2MAPK1PPIBNPC1 | |
| SCHEMBL8020823 | 0.88 | SMN1; SMN2 (0.40) | PDE5ASMN1; SMN2MAPK1PPIBNPC1 | |
| SCHEMBL8033859 | 0.88 | SMN1; SMN2 (0.44) | PDE5ASMN1; SMN2MAPK1PPIBNPC1 | |
| SCHEMBL8029961 | 0.87 | KMT2A (0.38) | SMN1; SMN2MAPK1NPC1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985660-A1 | AMINOPHENOL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-03-15 | — | — | EP | disclosed |