Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | PPIB | P23284 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8020564 | 0.94 | KDM4E (0.37) | KDM4EALDH1A1L3MBTL1SMN1; SMN2PARP1 | |
| SCHEMBL8020628 | 0.92 | KMT2A (0.42) | KDM4EALDH1A1SMN1; SMN2HTTNPC1 | |
| SCHEMBL8031875 | 0.92 | MAPK1 (0.40) | SMN1; SMN2PDE5AMAPK1HTTKMT2A | |
| SCHEMBL27487707 | 0.91 | KDM4E (0.35) | KDM4EALDH1A1L3MBTL1SMN1; SMN2PARP1 | |
| SCHEMBL8020901 | 0.90 | SMN1; SMN2 (0.37) | KDM4ESMN1; SMN2PDE5AMAPK1PPIB | |
| SCHEMBL8031868 | 0.90 | PPIB (0.38) | SMN1; SMN2PDE5AMAPK1PPIBHTT | |
| SCHEMBL8033859 | 0.89 | SMN1; SMN2 (0.44) | SMN1; SMN2PDE5AMAPK1PPIBHTT | |
| SCHEMBL8020574 | 0.89 | PTGDR2 (0.38) | SMN1; SMN2PDE5AMAPK1PPIBHTT | |
| SCHEMBL8030212 | 0.89 | KMT2A (0.40) | SMN1; SMN2PARP1LRRK2MAPK1PPIB | |
| SCHEMBL8020736 | 0.89 | ITGB1 (0.36) | KDM4ESMN1; SMN2PDE5AMAPK1PPIB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985660-A1 | AMINOPHENOL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-03-15 | — | — | EP | disclosed |