SCHEMBL8020696

SCHEMBL8020696

CCCCCCCC/C=C\CCCCCCCCOCCC(NC(=O)CCCN(CCO)CCO)OCCCCCCCC/C=C\CCCCCCCC

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 2/20 0.44
CNR2 P34972 2/20 0.44
DEGS1 O15121 1/20 0.43
ALDH1A1 P00352 4/20 0.41
CNR1 P21554 2/20 0.41
HPGD P15428 2/20 0.41
BLM P54132 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
MEN1 O00255 1/20 0.41
MAPT P10636 1/20 0.41
ALOX12 P18054 1/20 0.41
KMT2A Q03164 1/20 0.41
KCNK3 O14649 1/20 0.41
THRB P10828 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8020705 1.00 TRPV1 (0.44) TRPV1CNR2DEGS1ALDH1A1CNR1
SCHEMBL8016945 0.92 DEGS1 (0.42) TRPV1CNR2DEGS1ALDH1A1BLM
SCHEMBL8016952 0.92 DEGS1 (0.42) TRPV1CNR2DEGS1ALDH1A1BLM
SCHEMBL8004471 0.89 DEGS1 (0.43) TRPV1CNR2DEGS1ALDH1A1BLM
SCHEMBL8004466 0.89 DEGS1 (0.43) TRPV1CNR2DEGS1ALDH1A1BLM
SCHEMBL8020701 0.80 PRKCA (0.47) TRPV1CNR2DEGS1ALDH1A1MEN1
SCHEMBL8004843 0.80 TLR2 (0.59) TRPV1CNR2ALDH1A1CNR1HPGD
SCHEMBL8004637 0.79 DEGS1 (0.40) TRPV1CNR2DEGS1ALDH1A1BLM
SCHEMBL8004646 0.79 DEGS1 (0.40) TRPV1CNR2DEGS1ALDH1A1BLM
SCHEMBL29283697 0.77 MEN1 (0.50) CNR2ALDH1A1CNR1MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0685234-B1 DRUG COMPOSITION CONTAINING NUCLEIC ACID COPOLYMER NIPPON SHINYAKU CO LTD (JP) 2000-05-10 EP disclosed
US-6020317-A Glycerol derivative, device and pharmaceutical composition NIPPON SHINYAKU CO. LTD. (JP) 2000-02-01 US disclosed
US-5705188-A LIPID MIXTURE, ANTITUMOR AGENTS NIPPON SHINYAKU COMPANY, LTD. (JP) 1998-01-06 US disclosed
EP-0685457-A1 GLYCEROL DERIVATIVE, DEVICE AND PHARMACEUTICAL COMPOSITION NIPPON SHINYAKU COMPANY, LIMITED (JP) 1995-12-06 EP disclosed
EP-0685234-A1 DRUG COMPOSITION CONTAINING NUCLEIC ACID COPOLYMER NIPPON SHINYAKU COMPANY, LIMITED (JP) 1995-12-06 EP disclosed