SCHEMBL8020701

SCHEMBL8020701

CCCCCCCCC=CCCCCCCCC(=O)OCCC(NC(=O)CCCN(CCO)CCO)OC(=O)CCCCCCCC=CCCCCCCCC

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 2/20 0.47
PRKCE Q02156 1/20 0.47
PRKCQ Q04759 1/20 0.47
PRKCD Q05655 1/20 0.47
DEGS1 O15121 1/20 0.47
MGLL Q99685 1/20 0.46
EPHX2 P34913 1/20 0.45
CNR2 P34972 2/20 0.45
TRPV1 Q8NER1 1/20 0.45
DGKA P23743 1/20 0.44
CETP P11597 3/20 0.43
THRB P10828 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
ALDH1A1 P00352 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8016949 0.92 PRKCA (0.47) PRKCAPRKCEPRKCQPRKCDDEGS1
SCHEMBL8004467 0.89 DNM1 (0.50) PRKCAPRKCEPRKCQPRKCDDEGS1
SCHEMBL15939615 0.81 MGLL (0.60) PRKCAPRKCEPRKCQPRKCDMGLL
SCHEMBL15939618 0.81 MGLL (0.60) PRKCAPRKCEPRKCQPRKCDMGLL
SCHEMBL8020705 0.80 TRPV1 (0.44) DEGS1CNR2TRPV1THRBMEN1
SCHEMBL8020696 0.80 TRPV1 (0.44) DEGS1CNR2TRPV1THRBMEN1
SCHEMBL8004640 0.80 PRKCA (0.44) PRKCAPRKCEPRKCQPRKCDDEGS1
SCHEMBL24728761 0.80 MGLL (0.59) PRKCAPRKCEPRKCQPRKCDMGLL
SCHEMBL20138973 0.80 MGLL (0.59) PRKCAPRKCEPRKCQPRKCDMGLL
SCHEMBL28424646 0.79 MGLL (0.62) PRKCAPRKCEPRKCQPRKCDMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0685234-B1 DRUG COMPOSITION CONTAINING NUCLEIC ACID COPOLYMER NIPPON SHINYAKU CO LTD (JP) 2000-05-10 EP disclosed
US-6020317-A Glycerol derivative, device and pharmaceutical composition NIPPON SHINYAKU CO. LTD. (JP) 2000-02-01 US disclosed
US-5705188-A LIPID MIXTURE, ANTITUMOR AGENTS NIPPON SHINYAKU COMPANY, LTD. (JP) 1998-01-06 US disclosed
EP-0685457-A1 GLYCEROL DERIVATIVE, DEVICE AND PHARMACEUTICAL COMPOSITION NIPPON SHINYAKU COMPANY, LIMITED (JP) 1995-12-06 EP disclosed
EP-0685234-A1 DRUG COMPOSITION CONTAINING NUCLEIC ACID COPOLYMER NIPPON SHINYAKU COMPANY, LIMITED (JP) 1995-12-06 EP disclosed