Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | USP5 | P45974 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | QDPR | P09417 | 1/20 | 0.30 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8020721 | 1.00 | HTR2A (0.37) | HTR2AHTR2CHTR2BADRA1AKDM1A | |
| SCHEMBL8030143 | 0.91 | HTR2A (0.35) | HTR2AHTR2CHTR2BADRA1AKDM1A | |
| SCHEMBL8030136 | 0.91 | HTR2A (0.35) | HTR2AHTR2CHTR2BADRA1AKDM1A | |
| SCHEMBL8030139 | 0.91 | HTR2A (0.35) | HTR2AHTR2CHTR2BADRA1AKDM1A | |
| SCHEMBL8398342 | 0.88 | P2RY14 (0.33) | HTR2AHTR2CHTR2BKDM1A | |
| SCHEMBL8398345 | 0.88 | P2RY14 (0.33) | HTR2AHTR2CHTR2BKDM1A | |
| SCHEMBL8084502 | 0.87 | SPHK1 (0.37) | HTR2AHTR2CHTR2BADRA1AGRIA4 | |
| SCHEMBL8084504 | 0.87 | SPHK1 (0.37) | HTR2AHTR2CHTR2BADRA1AGRIA4 | |
| SCHEMBL8440158 | 0.86 | ADRA1A (0.35) | HTR2AHTR2CHTR2BADRA1AKDM1A | |
| SCHEMBL8440156 | 0.86 | ADRA1A (0.35) | HTR2AHTR2CHTR2BADRA1AKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0718301-B1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 2000-03-08 | — | — | EP | disclosed |
| US-5679746-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-10-21 | — | — | US | disclosed |
| EP-0718301-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-06-26 | — | — | EP | disclosed |