Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY14 | Q15391 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 3/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8398345 | 1.00 | P2RY14 (0.33) | P2RY14CYP17A1CYP11B2CYP11B1HTR2A | |
| SCHEMBL7766440 | 0.89 | DAO (0.32) | — | |
| SCHEMBL7766436 | 0.89 | DAO (0.32) | — | |
| SCHEMBL7758916 | 0.88 | PDE5A (0.36) | P2RY14CYP17A1CYP11B2CYP11B1 | |
| SCHEMBL7758913 | 0.88 | PDE5A (0.36) | P2RY14CYP17A1CYP11B2CYP11B1 | |
| SCHEMBL8020717 | 0.88 | HTR2A (0.37) | HTR2AHTR2CHTR2BKDM1A | |
| SCHEMBL8020721 | 0.88 | HTR2A (0.37) | HTR2AHTR2CHTR2BKDM1A | |
| SCHEMBL7757568 | 0.84 | CYP11B2 (0.34) | P2RY14CYP17A1CYP11B2CYP11B1HTR2A | |
| SCHEMBL7757564 | 0.84 | CYP11B2 (0.34) | P2RY14CYP17A1CYP11B2CYP11B1HTR2A | |
| SCHEMBL7756306 | 0.84 | P2RY14 (0.32) | P2RY14CYP17A1CYP11B2CYP11B1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650969-B1 | A Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 1999-05-26 | — | — | EP | disclosed |
| US-5659059-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-08-19 | — | — | US | disclosed |
| EP-0650969-A1 | A Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-05-03 | — | — | EP | disclosed |