Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.42 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11800387 | 0.84 | HPGD (0.51) | MAPTCYP1A2CYP2C19CYP2C9HTT | |
| SCHEMBL28388931 | 0.84 | RAB9A (0.53) | MAPTCYP1A2HSD17B10MAPK1POLB | |
| SCHEMBL11811090 | 0.84 | ALDH1A1 (0.51) | MAPTCYP3A4GAAMEN1KMT2A | |
| SCHEMBL11592483 | 0.82 | MAPT (0.49) | MAPTCYP3A4HSD17B10HTTGAA | |
| SCHEMBL11079274 | 0.79 | MAPT (0.58) | MAPTCYP1A2CYP3A4CYP2C19HSD17B10 | |
| SCHEMBL8601662 | 0.78 | MAPT (0.56) | MAPTCYP1A2CYP3A4CYP2C19HSD17B10 | |
| SCHEMBL24307977 | 0.76 | MAPT (0.55) | MAPTCYP1A2CYP3A4CYP2C19HSD17B10 | |
| SCHEMBL2492535 | 0.75 | MAPT (0.62) | MAPTCYP1A2CYP3A4CYP2C19HSD17B10 | |
| SCHEMBL31258062 | 0.75 | MAPT (0.62) | MAPTCYP1A2CYP3A4CYP2C19HSD17B10 | |
| SCHEMBL10994611 | 0.75 | HSD17B10 (0.53) | MAPTCYP3A4HSD17B10HTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6099625-A | Ink composition | ZENECA LIMITED (GB) | 2000-08-08 | — | — | US | disclosed |
| EP-0823927-A2 | INK COMPOSITION | ZENECA LIMITED (GB) | 1998-02-18 | — | — | EP | disclosed |
| WO-1996034916-A2 | INK COMPOSITION | ZENECA LIMITED (GB) | 1996-11-07 | — | — | WO | disclosed |