Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 2/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | BDKRB2 | P30411 | 9/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8036098 | 0.99 | CASR (0.44) | CASREPHX1EPHX2BDKRB2ALDH1A1 | |
| SCHEMBL8020624 | 0.94 | BDKRB2 (0.42) | CASREPHX1EPHX2BDKRB2ALDH1A1 | |
| SCHEMBL8020609 | 0.94 | EPHX1 (0.42) | CASREPHX1EPHX2BDKRB2ALDH1A1 | |
| SCHEMBL8030264 | 0.94 | CASR (0.49) | CASREPHX1EPHX2BDKRB2ALDH1A1 | |
| SCHEMBL8033869 | 0.93 | BDKRB2 (0.42) | CASREPHX1EPHX2BDKRB2ALDH1A1 | |
| SCHEMBL8031837 | 0.93 | EPHX1 (0.40) | CASREPHX1EPHX2BDKRB2ALDH1A1 | |
| SCHEMBL8029962 | 0.93 | CASR (0.48) | CASREPHX2BDKRB2ALDH1A1MAPT | |
| SCHEMBL8030643 | 0.90 | CASR (0.46) | CASREPHX2BDKRB2ALDH1A1MAPT | |
| SCHEMBL8030224 | 0.90 | CASR (0.45) | CASREPHX2BDKRB2ALDH1A1MAPT | |
| SCHEMBL8020853 | 0.90 | CASR (0.45) | CASREPHX2BDKRB2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985660-A1 | AMINOPHENOL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-03-15 | — | — | EP | disclosed |