Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | PPIB | P23284 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | BDKRB2 | P30411 | 5/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8030385 | 0.94 | BDKRB2 (0.41) | KMT2AGAAMEN1MAPK1NTSR1 | |
| SCHEMBL8036825 | 0.92 | BDKRB2 (0.42) | KMT2AGAAMEN1MAPK1NTSR1 | |
| SCHEMBL8020963 | 0.91 | KMT2A (0.41) | KMT2AGAAMEN1MAPK1NTSR1 | |
| SCHEMBL8030026 | 0.91 | BDKRB2 (0.43) | KMT2AGAAMEN1MAPK1NTSR1 | |
| SCHEMBL8020734 | 0.91 | KMT2A (0.40) | KMT2AGAAMEN1MAPK1NTSR1 | |
| SCHEMBL8030135 | 0.90 | KMT2A (0.39) | KMT2AGAAMEN1MAPK1NTSR1 | |
| SCHEMBL8036298 | 0.90 | KMT2A (0.42) | KMT2AGAAMEN1MAPK1NTSR1 | |
| SCHEMBL8032087 | 0.90 | KMT2A (0.38) | KMT2AGAAMEN1MAPK1NTSR1 | |
| SCHEMBL8033965 | 0.90 | KMT2A (0.42) | KMT2AGAAMEN1MAPK1NTSR1 | |
| SCHEMBL8036472 | 0.89 | KMT2A (0.39) | KMT2AGAAMEN1MAPK1NTSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985660-A1 | AMINOPHENOL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-03-15 | — | — | EP | disclosed |