Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8030284 | 0.95 | MAPT (0.46) | BDKRB2MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL8030385 | 0.93 | BDKRB2 (0.41) | BDKRB2MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8020864 | 0.92 | KMT2A (0.39) | BDKRB2ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8020963 | 0.90 | KMT2A (0.41) | BDKRB2MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8030026 | 0.89 | BDKRB2 (0.43) | BDKRB2MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8020734 | 0.89 | KMT2A (0.40) | BDKRB2KMT2AMEN1SMN1; SMN2GAA | |
| SCHEMBL8033965 | 0.88 | KMT2A (0.42) | BDKRB2KMT2AMEN1SMN1; SMN2GAA | |
| SCHEMBL8032087 | 0.88 | KMT2A (0.38) | BDKRB2KMT2AMEN1SMN1; SMN2GAA | |
| SCHEMBL8036298 | 0.88 | KMT2A (0.42) | BDKRB2KMT2AMEN1SMN1; SMN2GAA | |
| SCHEMBL8030366 | 0.88 | ALDH1A1 (0.38) | BDKRB2MAPTALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985660-A1 | AMINOPHENOL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-03-15 | — | — | EP | disclosed |