SCHEMBL8020920

SCHEMBL8020920

CC=C(Sc1cccc(CC=NOCc2ccccc2)c1)C(=O)OC

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.35
KMT2A Q03164 2/20 0.35
HIF1A Q16665 1/20 0.34
PKM P14618 2/20 0.33
LMNA P02545 3/20 0.32
USP2 O75604 1/20 0.32
NAMPT P43490 1/20 0.32
HPGD P15428 2/20 0.32
PPARG P37231 1/20 0.32
PPARA Q07869 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
MAPT P10636 1/20 0.32
PTGER4 P35408 1/20 0.32
PTGER2 P43116 1/20 0.32
MTNR1A P48039 1/20 0.31
MTNR1B P49286 1/20 0.31
FKBP1A P62942 1/20 0.31
NPC1 O15118 2/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8020916 0.92 ALDH1A1 (0.34) ALDH1A1KMT2AHIF1APKMLMNA
SCHEMBL8020546 0.74 ALDH1A1 (0.36) ALDH1A1KMT2APKML3MBTL1MAPT
SCHEMBL8020542 0.71 ALDH1A1 (0.35) ALDH1A1KMT2APKML3MBTL1MAPT
SCHEMBL8020891 0.70 MAPT (0.41) ALDH1A1KMT2APKML3MBTL1MAPT
SCHEMBL10691482 0.69 IDO1 (0.46) ALDH1A1KMT2ALMNAHPGDPPARG
SCHEMBL7966098 0.69 IDO1 (0.46) ALDH1A1KMT2ALMNAHPGDPPARG
SCHEMBL8009800 0.69 ALDH1A1 (0.40) ALDH1A1KMT2APKMLMNAHPGD
SCHEMBL8009445 0.68 MEN1 (0.40) ALDH1A1KMT2ALMNAHPGDL3MBTL1
SCHEMBL8020576 0.67 PPARG (0.45) HPGDPPARGPPARAL3MBTL1NPC1
SCHEMBL8020914 0.67 MEN1 (0.34) ALDH1A1KMT2AHIF1APPARGMTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975587-A1 OXIME ETHER COMPOUNDS, THEIR USE AND INTERMEDIATES FOR PREPARATIONS OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-02-02 EP disclosed
WO-1998043949-A1 OXIME ETHER COMPOUNDS, THEIR USE AND INTERMEDIATES FOR PREPARATIONS OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-10-08 WO disclosed