SCHEMBL8020928

SCHEMBL8020928

CC=C(Oc1cccc(CC=NO)c1)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CTBP2 P56545 2/20 0.43
ACHE P22303 6/20 0.37
KMT2A Q03164 4/20 0.37
MEN1 O00255 3/20 0.37
CYP1A2 P05177 1/20 0.35
ALDH1A1 P00352 2/20 0.34
KDM4E B2RXH2 1/20 0.34
CYP11B1 P15538 1/20 0.34
CYP11B2 P19099 1/20 0.34
EPOR P19235 1/20 0.34
MTNR1A P48039 1/20 0.34
MTNR1B P49286 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8020925 0.88 CTBP2 (0.43) CTBP2ACHEKMT2AMEN1CYP1A2
SCHEMBL8022472 0.87 CTBP2 (0.41) CTBP2ACHEKMT2AMEN1CYP1A2
SCHEMBL13433917 0.81 SMN1; SMN2 (0.48) CTBP2ACHEKMT2AMEN1CYP1A2
SCHEMBL8022470 0.80 CTBP2 (0.37) CTBP2ACHEKMT2AMEN1ALDH1A1
SCHEMBL1004802 0.72 ATM (0.44) ALDH1A1KDM4E
SCHEMBL1004800 0.72 ATM (0.44) ALDH1A1KDM4E
SCHEMBL7777015 0.71 FFAR1 (0.41) CTBP2ALDH1A1KDM4E
SCHEMBL2635745 0.70 FOLH1 (0.56) KMT2A
SCHEMBL28745456 0.70 FOLH1 (0.56) KMT2A
SCHEMBL16167356 0.70 CYP3A4 (0.51) ACHEKMT2AMEN1MTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975587-A1 OXIME ETHER COMPOUNDS, THEIR USE AND INTERMEDIATES FOR PREPARATIONS OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-02-02 EP disclosed
WO-1998043949-A1 OXIME ETHER COMPOUNDS, THEIR USE AND INTERMEDIATES FOR PREPARATIONS OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-10-08 WO disclosed