SCHEMBL1004800

SCHEMBL1004800

C/C=C(\Oc1ccccc1)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
HPGD P15428 1/20 0.42
ALOX15 P16050 1/20 0.42
HSD17B10 Q99714 1/20 0.42
ELANE P08246 1/20 0.42
AKR1C3 P42330 1/20 0.42
MAPT P10636 3/20 0.42
ALDH1A1 P00352 2/20 0.42
MAOB P27338 1/20 0.41
RAD51 Q06609 1/20 0.41
BCHE P06276 1/20 0.41
GAA P10253 2/20 0.40
KDM4E B2RXH2 1/20 0.40
HSP90AA1 P07900 1/20 0.40
NSD2 O96028 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1004802 1.00 ATM (0.44) ATML3MBTL1TDP1HPGDALOX15
SCHEMBL15508892 0.88 GAA (0.51) TDP1ALOX15HSD17B10ELANEMAPT
SCHEMBL15515753 0.88 GAA (0.51) TDP1ALOX15HSD17B10ELANEMAPT
SCHEMBL1006524 0.83 AKR1C3 (0.48) ATML3MBTL1TDP1HPGDALOX15
SCHEMBL6463471 0.82 ATM (0.40) ATML3MBTL1TDP1HPGDALOX15
SCHEMBL11547869 0.81 LMNA (0.49) L3MBTL1TDP1HPGDHSD17B10ALDH1A1
SCHEMBL11570625 0.81 LMNA (0.49) L3MBTL1TDP1HPGDHSD17B10ALDH1A1
SCHEMBL8228620 0.81 TDP1 (0.42) ATML3MBTL1TDP1HPGDALOX15
SCHEMBL10792060 0.81 TDP1 (0.42) ATML3MBTL1TDP1HPGDALOX15
SCHEMBL9685241 0.81 TDP1 (0.42) ATML3MBTL1TDP1HPGDALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2275398-B1 APPLICATION OF AN IRIDIUM COMPLEX IN ASYMMETRIC CATALYTIC HYDROGENATION OF AN UNSATURATED CARBOXYLIC ACID ZHEJIANG JIUZHOU PHARM CO LTD (CN) 2016-05-04 EP claimed
US-20110092732-A1 APPLICATION OF IRIDIUM COMPLEXES IN ASYMMETRIC CATALYTIC HYDROGENATION OF UNSATURATED CARBOXYLIC ACIDS Zheijiang Jiuzhou Pharmaceutical Co., Ltd. (CN) 2011-04-21 US claimed
EP-2275398-A1 APPLICATION OF THE IRIDIUM COMPLEX IN ASYMMETRIC CATALYTIC HYDROGENATION FOR UNSATURATED CARBOXYLIC ACID Zhejiang Jiuzhou Pharmaceutical Co., Ltd. (CN) 2011-01-19 EP claimed
US-11931365-B2 Use of PPAR-delta agonists in the treatment of disease RENEO PHARMACEUTICALS, INC. (US) 2024-03-19 US disclosed
US-20240016809-A1 USE OF PPAR-DELTA AGONISTS IN THE TREATMENT OF DISEASE RENEO PHARMACEUTICALS, INC. 2024-01-18 US disclosed
WO-2023147309-A1 USE OF PPAR-DELTA AGONISTS IN THE TREATMENT OF DISEASE RENEO PHARMACEUTICALS, INC. (US) 2023-08-03 WO disclosed
US-20230233570-A1 USE OF PPAR-DELTA AGONISTS IN THE TREATMENT OF DISEASE RENEO PHARMACEUTICALS, INC. 2023-07-27 US disclosed
US-11566140-B2 Exterior coating composition TROY CORPORATION (US) 2023-01-31 US disclosed
US-20220370467-A1 USING OF A PPAR-DELTA AGONIST IN THE TREATMENT OF KIDNEY DISEASE WASHINGTON UNIVERSITY 2022-11-24 US disclosed
EP-4031124-A1 USE OF A PPAR-DELTA AGONIST IN THE TREATMENT OF KIDNEY DISEASE Reneo Pharmaceuticals, Inc. (US) 2022-07-27 EP disclosed
CN-114727976-A Use of PPAR-delta agonists in the treatment of renal disease 雷内奥制药公司 2022-07-08 CN disclosed
US-20110092732-A1 APPLICATION OF IRIDIUM COMPLEXES IN ASYMMETRIC CATALYTIC HYDROGENATION OF UNSATURATED CARBOXYLIC ACIDS Zheijiang Jiuzhou Pharmaceutical Co., Ltd. (CN) 2011-04-21 US disclosed
US-20110092732-A1 APPLICATION OF IRIDIUM COMPLEXES IN ASYMMETRIC CATALYTIC HYDROGENATION OF UNSATURATED CARBOXYLIC ACIDS Zheijiang Jiuzhou Pharmaceutical Co., Ltd. (CN) 2011-04-21 US disclosed
US-20110092732-A1 APPLICATION OF IRIDIUM COMPLEXES IN ASYMMETRIC CATALYTIC HYDROGENATION OF UNSATURATED CARBOXYLIC ACIDS Zheijiang Jiuzhou Pharmaceutical Co., Ltd. (CN) 2011-04-21 US disclosed
EP-2275398-A1 APPLICATION OF THE IRIDIUM COMPLEX IN ASYMMETRIC CATALYTIC HYDROGENATION FOR UNSATURATED CARBOXYLIC ACID Zhejiang Jiuzhou Pharmaceutical Co., Ltd. (CN) 2011-01-19 EP disclosed
EP-2275398-A1 APPLICATION OF THE IRIDIUM COMPLEX IN ASYMMETRIC CATALYTIC HYDROGENATION FOR UNSATURATED CARBOXYLIC ACID Zhejiang Jiuzhou Pharmaceutical Co., Ltd. (CN) 2011-01-19 EP disclosed
EP-2105432-A1 Process for Producing Chromone Compound Sumitomo Chemical Company, Limited (JP) 2009-09-30 EP disclosed
US-6846777-B2 Synergistic biocidal composition THOR GMBH (DE) 2005-01-25 US disclosed
US-20030199490-A1 Synergistic biocidal composition THOR GMBH (DE) 2003-10-23 US disclosed
US-4661617-A PESTICIDES SANDOZ LTD. (CH) 1987-04-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220370467-A1 USING OF A PPAR-DELTA AGONIST IN THE TREATMENT OF KIDNEY DISEASE PPARG, PPARA, PPARD ATM 1188/4885L3MBTL1 3816/4885TDP1 4243/4885
US-11931365-B2 Use of PPAR-delta agonists in the treatment of disease PPARG, PPARD, PPARA ATM 4161/4885L3MBTL1 4028/4885TDP1 3595/4885
US-20110092732-A1 APPLICATION OF IRIDIUM COMPLEXES IN ASYMMETRIC CATALYTIC HYDROGENATION OF UNSATURATED CARBOXYLIC ACIDS HDHD5, ELOVL5, FASN ATM 4182/4885L3MBTL1 4329/4885TDP1 4705/4885
US-20230233570-A1 USE OF PPAR-DELTA AGONISTS IN THE TREATMENT OF DISEASE PPARG, PPARD, PPARA ATM 4161/4885L3MBTL1 4028/4885TDP1 3595/4885
US-20240016809-A1 USE OF PPAR-DELTA AGONISTS IN THE TREATMENT OF DISEASE PPARG, PPARD, PPARA ATM 4161/4885L3MBTL1 4028/4885TDP1 3595/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.