Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.47 |
| ▸ | PPARA | Q07869 | 5/20 | 0.47 |
| ▸ | BACE1 | P56817 | 3/20 | 0.46 |
| ▸ | DHODH | Q02127 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | OSBP | P22059 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8027818 | 0.85 | BACE1 (0.46) | BACE1DHODHMAOBOSBPALOX5 | |
| SCHEMBL8027423 | 0.84 | BACE1 (0.67) | BACE1DHODHMAOBALOX5ALOX15 | |
| SCHEMBL8011239 | 0.82 | PPARG (0.62) | PPARGPPARABACE1MAOBOSBP | |
| SCHEMBL8009546 | 0.82 | PPARG (0.62) | PPARGPPARABACE1MAOBOSBP | |
| SCHEMBL8011251 | 0.81 | PPARG (0.63) | PPARGPPARABACE1MAOBOSBP | |
| SCHEMBL1587344 | 0.71 | AKR1B10 (0.66) | PPARGPPARAMAOBAKR1B10AKR1B1 | |
| SCHEMBL8017471 | 0.67 | ALOX5 (0.59) | PPARGPPARABACE1MAOBOSBP | |
| Geranylgeranylhydroquinone SCHEMBL8025990 | 0.67 | ALOX5 (0.59) | PPARGPPARABACE1MAOBOSBP | |
| SCHEMBL31536036 | 0.67 | ALOX5 (0.59) | PPARGPPARABACE1MAOBOSBP | |
| SCHEMBL2943955 | 0.67 | ALOX5 (0.59) | PPARGPPARABACE1MAOBOSBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009098287-A1 | PHENYL-PRENYL DERIVATIVES, OF MARINE AND SYNTHETIC ORIGIN, FOR THE TREATMENT OF COGNITIVE, NEURODEGENERATIVE OR NEURONAL DISEASES OR DISORDERS | NOSCIRA S.A. (ES) | 2009-08-13 | — | — | WO | disclosed |