Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | PPID | Q08752 | 2/20 | 0.39 |
| ▸ | PPIB | P23284 | 1/20 | 0.39 |
| ▸ | PPIA | P62937 | 1/20 | 0.39 |
| ▸ | PPIG | Q13427 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 2/20 | 0.39 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.39 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8021278 | 1.00 | GAA (0.45) | GAASLC7A5MGAMSIMGAM2 | |
| Bromide SCHEMBL9807038 | 0.98 | GAA (0.44) | GAASLC7A5MGAMSIMGAM2 | |
| Hydrochloric Acid SCHEMBL9807062 | 0.98 | GAA (0.44) | GAASLC7A5MGAMSIMGAM2 | |
| SCHEMBL10954445 | 0.84 | SLC7A5 (0.45) | SLC7A5ANPEPRNPEPDNPEPTSHR | |
| SCHEMBL14031294 | 0.84 | GAA (0.49) | GAAMGAMSIMGAM2PPID | |
| SCHEMBL10954441 | 0.84 | SLC7A5 (0.45) | SLC7A5ANPEPRNPEPDNPEPTSHR | |
| SCHEMBL5494766 | 0.84 | ANPEP (0.41) | GAASLC7A5MGAMSIMGAM2 | |
| SCHEMBL5494763 | 0.84 | ANPEP (0.41) | GAASLC7A5MGAMSIMGAM2 | |
| SCHEMBL29907351 | 0.83 | GAA (0.45) | GAAMGAMSIMGAM2PPID | |
| Hydrochloric Acid SCHEMBL10790535 | 0.83 | SLC7A5 (0.44) | SLC7A5ANPEPRNPEPDNPEPTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10207990-B2 | Salts and prodrugs of 1-methyl-D-tryptophan | NEWLINK GENETICS CORPORATION (US) | 2019-02-19 | — | — | US | disclosed |
| US-20180134658-A1 | SALTS AND PRODRUGS OF 1-METHYL-D-TRYPTOPHAN | LUMOS PHARMA, INC. | 2018-05-17 | — | — | US | disclosed |
| EP-0985932-A1 | METHOD FOR EXAMINING CHRONIC REJECTION REACTIONS FOLLOWING ORGAN TRANSPLANTATION AND METHOD FOR DETERMINING URINE COMPONENTS | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2000-03-15 | — | — | EP | disclosed |
| US-4545810-A | Herbicidal and plant growth regulant diphenylpyridazinones | SDS BIOTECH CORPORATION (US) | 1985-10-08 | — | — | US | disclosed |
| WO-1982000402-A1 | HERBICIDAL AND PLANT GROWTH REGULANT DIPHENYLPYRIDAZINONES | DIAMOND SHAMROCK CORP (US) | 1982-02-18 | — | — | WO | disclosed |
| EP-0046069-A1 | Herbicidal and plant growth regulant diphenylpyridazinones | DIAMOND SHAMROCK CORPORATION (US) | 1982-02-17 | — | — | EP | disclosed |
| US-RE30496-E | Tripeptide derivatives with central nervous system activity and preparation thereof | AYERST, MCKENNA & HARRISON, LTD. (CA) | 1981-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10207990-B2 | Salts and prodrugs of 1-methyl-D-tryptophan | IDO1, IDO2, INMT | GAA 3198/4885SLC7A5 371/4885MGAM 1778/4885 |
| US-20180134658-A1 | SALTS AND PRODRUGS OF 1-METHYL-D-TRYPTOPHAN | IDO1, IDO2, INMT | GAA 3198/4885SLC7A5 371/4885MGAM 1778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.