Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CFTR | P13569 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | MYC | P01106 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7186547 | 0.84 | ALDH1A1 (0.45) | KMT2AALDH1A1TDP1GAATSHR | |
| SCHEMBL4068453 | 0.84 | TSHR (0.50) | KMT2AALDH1A1TDP1GAATSHR | |
| Hydrogen Peroxide SCHEMBL28473316 | 0.83 | TSHR (0.57) | KMT2AALDH1A1TDP1GAATSHR | |
| SCHEMBL11274330 | 0.83 | TSHR (0.49) | KMT2AALDH1A1TDP1GAATSHR | |
| SCHEMBL11030148 | 0.83 | TSHR (0.49) | KMT2AALDH1A1TDP1GAATSHR | |
| SCHEMBL28323865 | 0.81 | TSHR (0.47) | KMT2AALDH1A1TDP1GAATSHR | |
| SCHEMBL9305621 | 0.81 | KDM4E (0.53) | KMT2AALDH1A1TDP1GAATSHR | |
| SCHEMBL254882 | 0.81 | TSHR (0.59) | KMT2AALDH1A1TDP1GAATSHR | |
| SCHEMBL996468 | 0.79 | TSHR (0.57) | KMT2AALDH1A1GAATSHRLMNA | |
| SCHEMBL8945914 | 0.79 | ALDH1A1 (0.79) | KMT2AALDH1A1TDP1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000030632-A1 | ARYL AND HETEROARYL COMPOUNDS USEFUL AS FIBROBLAST GROWTH FACTOR ANTAGONISTS | EISAI CO., LTD. (JP) | 2000-06-02 | — | — | WO | claimed |
| CN-105237560-B | A kind of LZC696 intermediates and its synthetic method | 上海博氏医药科技有限公司 | 2018-07-06 | — | — | CN | disclosed |
| US-7531573-B2 | potent, selective and safe inhibitors of the Ca2+-activated potassium channel | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2009-05-12 | — | — | US | disclosed |
| US-7531573-B2 | potent, selective and safe inhibitors of the Ca2+-activated potassium channel | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2009-05-12 | — | — | US | disclosed |
| WO-2000030632-A1 | ARYL AND HETEROARYL COMPOUNDS USEFUL AS FIBROBLAST GROWTH FACTOR ANTAGONISTS | EISAI CO., LTD. (JP) | 2000-06-02 | — | — | WO | disclosed |