Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8016126 | 1.00 | GPR119 (0.34) | GPR119CA2HTTHCRTR2F2 | |
| SCHEMBL8016127 | 1.00 | GPR119 (0.34) | GPR119CA2HTTHCRTR2F2 | |
| SCHEMBL8016132 | 1.00 | GPR119 (0.34) | GPR119CA2HTTHCRTR2F2 | |
| SCHEMBL8004608 | 0.97 | CA2 (0.35) | GPR119CA2HTTHCRTR2F2 | |
| SCHEMBL8013507 | 0.91 | GPR119 (0.33) | GPR119CA2HTTHCRTR2F2 | |
| SCHEMBL14274428 | 0.91 | HTT (0.37) | CA2HTTF2POLBKMT2A | |
| SCHEMBL8018347 | 0.89 | MAPT (0.37) | GPR119CA2HTTPOLBKMT2A | |
| SCHEMBL8013502 | 0.89 | KDM4E (0.33) | GPR119CA2HTTKMT2A | |
| SCHEMBL8014704 | 0.89 | MAPT (0.37) | GPR119CA2HTTPOLBKMT2A | |
| SCHEMBL8014695 | 0.89 | MAPT (0.37) | GPR119CA2HTTPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6149990-A | Carboxylate derivatives comprising an ether group and liquid crystal composition comprising the same | CHISSO CORPORATION (JP) | 2000-11-21 | — | — | US | disclosed |
| EP-0884302-A1 | CARBOXYLIC ESTER DERIVATIVES CONTAINING ETHER GROUP AND LIQUID-CRYSTAL COMPOSITION CONTAINING THE SAME | CHISSO CORPORATION (JP) | 1998-12-16 | — | — | EP | disclosed |