Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.70 |
| ▸ | PPARG | P37231 | 3/20 | 0.57 |
| ▸ | METAP1 | P53582 | 2/20 | 0.55 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.52 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.52 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.52 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16712246 | 0.86 | MAPK1 (0.63) | MAPK1KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL29323764 | 0.82 | MEN1 (1.00) | MAPK1KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL4037782 | 0.77 | METAP1 (0.76) | MAPK1KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL15421462 | 0.75 | METAP1 (0.73) | MAPK1KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL10134156 | 0.75 | SIRT2 (0.69) | MAPK1KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL16712247 | 0.74 | METAP1 (0.66) | MAPK1KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL14281294 | 0.74 | MEN1 (0.71) | MAPK1KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL10095183 | 0.74 | METAP1 (0.65) | MAPK1KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL14306896 | 0.72 | MEN1 (0.68) | MAPK1KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL12865929 | 0.72 | ALDH1A1 (0.66) | MAPK1KDM4EMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000052100-A1 | AGENTS FOR COLOURING FIBRES | WELLA AKTIENGESELLSCHAFT (DE) | 2000-09-08 | — | — | WO | disclosed |