Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 3/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | LIPE | Q05469 | 1/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8022176 | 1.00 | SGMS2 (0.52) | SGMS2HIF1ANPC1HTTGAA | |
| SCHEMBL8881918 | 0.89 | HIF1A (0.65) | SGMS2HIF1ANPC1HTTGAA | |
| SCHEMBL9694581 | 0.89 | HIF1A (0.65) | SGMS2HIF1ANPC1HTTGAA | |
| SCHEMBL8881912 | 0.89 | HIF1A (0.65) | SGMS2HIF1ANPC1HTTGAA | |
| SCHEMBL8954633 | 0.87 | SGMS2 (0.51) | SGMS2HIF1ANPC1HTTGAA | |
| SCHEMBL8880953 | 0.87 | HIF1A (0.48) | SGMS2HIF1ANPC1HTTGAA | |
| SCHEMBL8368335 | 0.87 | SGMS2 (0.51) | SGMS2HIF1ANPC1HTTGAA | |
| SCHEMBL8880949 | 0.87 | HIF1A (0.48) | SGMS2HIF1ANPC1HTTGAA | |
| SCHEMBL8368334 | 0.87 | SGMS2 (0.51) | SGMS2HIF1ANPC1HTTGAA | |
| SCHEMBL8020206 | 0.85 | HCRTR1 (0.51) | HTTGAAMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675133-B1 | 13-Substituted milbemycin derivatives, their preparation and use | SANKYO CO (JP) | 2000-01-12 | — | — | EP | disclosed |
| US-5614470-A | AGRICULTURAL ANTHELMINTIC, ACARICIDE, INSECTICIDE | SANKYO COMPANY, LIMITED (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0675133-A1 | 13-Substituted milbemycin derivatives, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1995-10-04 | — | — | EP | disclosed |