SCHEMBL8954633

SCHEMBL8954633

CNC(=O)/C(=N/OC)c1ccccc1OCc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SGMS2 Q8NHU3 4/20 0.51
HIF1A Q16665 1/20 0.51
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
NPC1 O15118 2/20 0.49
GAA P10253 2/20 0.48
LMNA P02545 1/20 0.46
MAPT P10636 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
ALDH1A1 P00352 1/20 0.46
HTT P42858 1/20 0.46
BRD4 O60885 1/20 0.46
KDM4E B2RXH2 1/20 0.45
RAB9A P51151 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8368335 1.00 SGMS2 (0.51) SGMS2HIF1AMEN1KMT2ANPC1
SCHEMBL8368334 1.00 SGMS2 (0.51) SGMS2HIF1AMEN1KMT2ANPC1
SCHEMBL8371724 0.88 HIF1A (0.51) HIF1AKMT2ANPC1L3MBTL1ALDH1A1
SCHEMBL8371725 0.88 HIF1A (0.51) HIF1AKMT2ANPC1L3MBTL1ALDH1A1
SCHEMBL8881912 0.87 HIF1A (0.65) SGMS2HIF1AMEN1KMT2ANPC1
SCHEMBL9694581 0.87 HIF1A (0.65) SGMS2HIF1AMEN1KMT2ANPC1
SCHEMBL8881918 0.87 HIF1A (0.65) SGMS2HIF1AMEN1KMT2ANPC1
SCHEMBL8022171 0.87 SGMS2 (0.52) SGMS2HIF1AMEN1KMT2ANPC1
SCHEMBL8022176 0.87 SGMS2 (0.52) SGMS2HIF1AMEN1KMT2ANPC1
SCHEMBL8369578 0.85 HIF1A (0.61) HIF1AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0398692-B1 Alkoxyiminoacetamide derivatives and their use as fungicides SHIONOGI & CO (JP) 1996-08-21 EP disclosed
US-5548078-A FOR AGRICULTURE SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1996-08-20 US disclosed
US-5401877-A Agricultural fungicide SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1995-03-28 US disclosed
EP-0629609-A1 Process for the preparation of Alkoxyiminoacetamide derivatives and an intermediate therefor SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) 1994-12-21 EP disclosed
US-5371222-A Intermediates SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1994-12-06 US disclosed
US-5371223-A Controlling phytopathogens SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1994-12-06 US disclosed
US-5185342-A ALKOXYIMINOACETAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1993-02-09 US disclosed
EP-0398692-A2 Alkoxyiminoacetamide derivatives and their use as fungicides SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) 1990-11-22 EP disclosed