Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL667669 | 0.79 | GFER (0.57) | GRM5GFER | |
| SCHEMBL8022200 | 0.76 | GFER (0.51) | GRM5GFERNPSR1 | |
| SCHEMBL1751529 | 0.73 | GFER (0.50) | GRM5GFER | |
| SCHEMBL2636049 | 0.72 | GFER (0.55) | GRM5GFER | |
| SCHEMBL6563747 | 0.71 | CA12 (0.51) | GRM5GFER | |
| SCHEMBL6772023 | 0.70 | GRM5 (0.46) | GRM5GFERNPSR1 | |
| SCHEMBL29941936 | 0.70 | GFER (0.47) | GRM5GFER | |
| SCHEMBL28909500 | 0.70 | GFER (0.47) | GRM5GFER | |
| SCHEMBL26343014 | 0.69 | GFER (0.46) | GRM5GFER | |
| SCHEMBL29961896 | 0.68 | GFER (0.48) | GRM5GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6069247-A | REACTING AN ACETYLENECARBOXY AMIDE AND AN ARYL OR HETEROCYCLYL HALIDE OR A GROUP ENHANCING THE ELECTROPHILICITY OF THE ATOM TO WHICH IT IS ATTACHED FOR DISPLACEMENT; USING A PALLADIUM COMPOUND CATALYST, A BASE AND AN ACID | ELI LILLY AND COMPANY (US) | 2000-05-30 | — | — | US | disclosed |