SCHEMBL8022285

SCHEMBL8022285

CCC(C)(C)OOOC(=O)CCCC(=O)OOOC(C)(C)CC

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.38
DGKA P23743 1/20 0.31
CYP1A2 P05177 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
RECQL P46063 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8031982 0.96 DGKA (0.35) TSHRDGKACYP1A2ALDH1A1TDP1
SCHEMBL9617938 0.94 DGKA (0.38) TSHRDGKAALDH1A1KDM4EMEN1
SCHEMBL7995222 0.94 DGKA (0.38) TSHRDGKAALDH1A1KDM4EMEN1
SCHEMBL28363410 0.92 MEN1 (0.38) TSHRDGKAALDH1A1KDM4EMEN1
SCHEMBL8022278 0.92 ALDH1A1 (0.33) TSHRALDH1A1TDP1KMT2A
SCHEMBL5463572 0.91 DGKA (0.44) TSHRDGKAALDH1A1
SCHEMBL7699787 0.89 DGKA (0.47) TSHRDGKAALDH1A1TDP1MEN1
SCHEMBL1069843 0.88 ALDH1A1 (0.43) TSHRALDH1A1TDP1
SCHEMBL29526099 0.88 DGKA (0.31) DGKA
SCHEMBL6659869 0.88 KDM4E (0.38) DGKATDP1KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000068192-A2 PROCESS FOR THE PREPARATION OF (DI)ALKYLPEROXY ESTERS OF (DI)CARBOXYLIC ACIDS AKZO NOBEL N.V. (NL) 2000-11-16 WO disclosed