SCHEMBL8022387

SCHEMBL8022387

CC1=CCc2ccccc2C1C

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 4/20 0.35
HTR2C P28335 1/20 0.35
HTR2B P41595 1/20 0.35
PRCP P42785 3/20 0.34
PDPK1 O15530 1/20 0.33
DRD2 P14416 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10789003 0.77 MEN1 (0.33)
SCHEMBL5751646 0.71 HTR2A (0.38) HTR2AHTR2CHTR2BPRCPPDPK1
SCHEMBL8746509 0.70 HTR2A (0.52) HTR2AHTR2CHTR2BPRCPPDPK1
SCHEMBL9633656 0.70 HTR2A (0.58) HTR2AHTR2C
SCHEMBL28950981 0.69 CES1 (0.33) DRD2
SCHEMBL11143438 0.67 BRD4 (0.41) HTR2AHTR2CHTR2BPRCPDRD2
SCHEMBL11143435 0.67 BRD4 (0.41) HTR2AHTR2CHTR2BPRCPDRD2
SCHEMBL2600798 0.65 HTR2A (0.37) HTR2AHTR2CHTR2BPRCPPDPK1
SCHEMBL11144393 0.64 CYP1A2 (0.58) HTR2AHTR2C
SCHEMBL18352989 0.64 HTR2A (0.45) HTR2AHTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5241089-A Polyhydrodimethylnaphthalene spirofuran derivatives, organoleptic uses thereof and process for preparing same INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1993-08-31 US claimed
US-5219835-A Polyhydrodimethylnaphthalene spirofuran derivatives, organoleptic uses thereof and process for preparing same INTERNATIONAL FLAVORS & FRAGRANCE INC. (US) 1993-06-15 US claimed
EP-1047654-A1 METHOD FOR PRODUCING 2,6-DMN FROM MIXED DIMETHYLNAPHTHALENES BY CRYSTALLIZATION, ADSORPTION AND ISOMERIZATION Chevron Chemical Company LLC (US) 2000-11-02 EP disclosed
US-6057487-A PRECIPITATION AND SEPARATION SUPERNATANT WITH 2,6-DIMETHYLNAPHTHALENE CHEVRON CHEMICAL COMPANY (US) 2000-05-02 US disclosed
WO-1999033770-A1 METHOD FOR PRODUCING 2,6-DMN FROM MIXED DIMETHYLNAPHTHALENES BY CRYSTALLIZATION, ADSORPTION AND ISOMERIZATION CHEVRON CHEMICAL COMPANY LLC (US) 1999-07-08 WO disclosed
US-5241089-A Polyhydrodimethylnaphthalene spirofuran derivatives, organoleptic uses thereof and process for preparing same INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1993-08-31 US disclosed
US-5241089-A Polyhydrodimethylnaphthalene spirofuran derivatives, organoleptic uses thereof and process for preparing same INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1993-08-31 US disclosed
US-5219835-A Polyhydrodimethylnaphthalene spirofuran derivatives, organoleptic uses thereof and process for preparing same INTERNATIONAL FLAVORS & FRAGRANCE INC. (US) 1993-06-15 US disclosed
US-5219835-A Polyhydrodimethylnaphthalene spirofuran derivatives, organoleptic uses thereof and process for preparing same INTERNATIONAL FLAVORS & FRAGRANCE INC. (US) 1993-06-15 US disclosed