Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 4/20 | 0.50 |
| ▸ | PPARG | P37231 | 14/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8033200 | 0.85 | KCNK3 (0.47) | KCNK3 | |
| SCHEMBL8034302 | 0.83 | POLB (0.45) | KCNK3PPARGHDAC1 | |
| SCHEMBL8028605 | 0.83 | POLB (0.45) | KCNK3PPARGHDAC1 | |
| SCHEMBL4537201 | 0.83 | PPARG (0.57) | KCNK3PPARGHDAC1 | |
| SCHEMBL4537762 | 0.83 | PPARG (0.48) | PPARGHDAC1 | |
| SCHEMBL8032490 | 0.82 | PPARG (0.55) | PPARGHDAC1 | |
| SCHEMBL4538247 | 0.80 | PPARG (0.59) | PPARG | |
| SCHEMBL8038740 | 0.80 | PPARG (0.57) | PPARG | |
| SCHEMBL8034326 | 0.79 | PPARG (0.48) | PPARG | |
| SCHEMBL8032181 | 0.79 | PPARG (0.59) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083526-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-09 | — | — | WO | disclosed |