Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 2/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.33 |
| ▸ | GSK3B | P49841 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | PLG | P00747 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL249804 | 0.88 | CCNE1 (0.31) | — | |
| SCHEMBL5725170 | 0.83 | ALDH1A1 (0.36) | — | |
| SCHEMBL8175087 | 0.72 | QDPR (0.39) | DYRK1AFAAH | |
| SCHEMBL18711979 | 0.71 | USP7 (0.37) | USP7NR1H4DYRK1AHRH4HRH3 | |
| SCHEMBL14243079 | 0.70 | NR1H4 (0.37) | USP7NR1H4DYRK1AGSK3BHRH4 | |
| Hydrochloric Acid SCHEMBL18689632 | 0.70 | USP7 (0.36) | USP7NR1H4DYRK1AHRH4HRH3 | |
| SCHEMBL411063 | 0.69 | RET (0.32) | — | |
| SCHEMBL19885770 | 0.69 | CCNE1 (0.33) | — | |
| SCHEMBL15133550 | 0.69 | CCNE1 (0.33) | — | |
| SCHEMBL14683656 | 0.68 | USP7 (0.43) | USP7NR1H4DYRK1AGSK3BHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009123992-A1 | OXYMETHYLENE ARYL COMPOUNDS AND USES THEREOF | METABOLEX, INC. (US) | 2009-10-08 | — | — | WO | disclosed |
| WO-2008083238-A2 | HETEROCYCLIC RECEPTOR AGONISTS FOR THE TREATMENT OF DIABETES AND METABOLIC DISORDERS | METABOLEX INC. (US) | 2008-07-10 | — | — | WO | disclosed |