Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PTPRC | P08575 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30687380 | 1.00 | NPC1 (0.46) | NPC1ALDH1A1RAB9ASMN1; SMN2CYP3A4 | |
| SCHEMBL671916 | 0.89 | CA1 (0.50) | NPC1ALDH1A1RAB9ASMN1; SMN2CYP3A4 | |
| SCHEMBL11743126 | 0.87 | ALDH1A1 (0.47) | NPC1ALDH1A1RAB9ASMN1; SMN2CYP3A4 | |
| SCHEMBL2272811 | 0.84 | ALDH1A1 (0.51) | NPC1ALDH1A1RAB9ASMN1; SMN2CYP3A4 | |
| SCHEMBL11882155 | 0.82 | AKT1 (0.44) | CA1CA2CA12CA9CA4 | |
| SCHEMBL8012548 | 0.82 | CA1 (0.51) | CA1CA2CA12CA9CA14 | |
| SCHEMBL27842438 | 0.80 | CA1 (0.54) | CA1CA2CA12CA9CA4 | |
| SCHEMBL8597605 | 0.80 | HDAC7 (0.45) | ALDH1A1LMNAPOLBHPGDALOX12 | |
| SCHEMBL28469382 | 0.80 | PTGES2 (0.51) | KMT2ACA1CA2CA12CA9 | |
| SCHEMBL672207 | 0.80 | CA1 (0.52) | NPC1ALDH1A1RAB9ASMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107635986-A | Substituted quinoxaline derivatives | 赛尔维他股份公司 | 2018-01-26 | — | — | CN | claimed |
| CN-117561081-A | Application of CYP450 inhibitor in inhibiting or killing mites and treating xerophthalmia | 广州珍实视界生物医药科技有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-114573586-B | Polycyclic compound for inhibiting Bruton tyrosine kinase activity, pharmaceutical composition and application thereof | 杭州和正医药有限公司 | 2023-11-03 | — | — | CN | disclosed |
| CN-110672843-A | Quintuplet time-resolved fluoroimmunoassay test strip for quantitatively determining sulfonamides | 南京海关动植物与食品检测中心 | 2020-01-10 | — | — | CN | disclosed |
| CN-108349282-A | Thermal recording medium and diphenyl sulphone (DPS) | 日本化药株式会社 | 2018-07-31 | — | — | CN | disclosed |
| CN-107635986-A | Substituted quinoxaline derivatives | 赛尔维他股份公司 | 2018-01-26 | — | — | CN | disclosed |
| CN-102958971-B | Epoxy polycyclopentadiene compounds | DOW GLOBAL TECHNOLOGIES INC | 2014-12-31 | — | — | CN | disclosed |
| CN-102958971-A | Epoxy polycyclopentadiene compounds | DOW GLOBAL TECHNOLOGIES LLC | 2013-03-06 | — | — | CN | disclosed |
| US-6127150-A | VECTOR FOR THE EFFICIENT EXPRESSION AND ISOLATION OF HETEROLOGOUS PROTEINS | BIONEBRASKA, INC. (US) | 2000-10-03 | — | — | US | disclosed |
| EP-0539530-B1 | PURIFICATION DIRECTED CLONING OF PEPTIDES | BIONEBRASKA INC (US) | 2000-02-02 | — | — | EP | disclosed |
| US-5595887-A | GENE EXPRESSION, FORMING POLYPEPTIDES FOR PROTEIN PURIFICATION | BIONEBRASKA, INC. (US) | 1997-01-21 | — | — | US | disclosed |
| US-5510387-A | ADMINISTERING A CRYSTALLINE GAMMA-MODIFICATION OF PARA-AMINOBENZENESULFANILAMIDE | Leonidov, Nikolai Borisovich (RU) | 1996-04-23 | — | — | US | disclosed |
| EP-0539530-A4 | PURIFICATION DIRECTED CLONING OF PEPTIDES. | — | 1993-09-15 | — | — | EP | disclosed |
| EP-0539530-A1 | PURIFICATION DIRECTED CLONING OF PEPTIDES | BIONEBRASKA, INC. (US) | 1993-05-05 | — | — | EP | disclosed |
| WO-1992001707-A1 | PURIFICATION DIRECTED CLONING OF PEPTIDES | BIONEBRASKA, INC. (US) | 1992-02-06 | — | — | WO | disclosed |
| CN-85101429-B | Microcapsules and process for making microcapsules | 斯多佛化学有限公司 | 1988-08-17 | — | — | CN | disclosed |
| CN-85101429-A | The process of microencapsulation and preparing microcapsules | — | 1987-01-17 | — | — | CN | disclosed |