SCHEMBL2272811

SCHEMBL2272811

Nc1ccc(S(=O)(=O)O)c(-c2ccccc2)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.51
TDP1 Q9NUW8 5/20 0.51
POLB P06746 3/20 0.51
L3MBTL1 Q9Y468 3/20 0.51
NSD2 O96028 2/20 0.51
KDM4E B2RXH2 2/20 0.51
GAA P10253 2/20 0.51
MAPT P10636 2/20 0.51
RECQL P46063 2/20 0.51
CASP6 P55212 2/20 0.51
APEX1 P27695 1/20 0.51
APOBEC3A P31941 1/20 0.51
APOBEC3G Q9HC16 1/20 0.51
PTGDR2 Q9Y5Y4 1/20 0.46
NPC1 O15118 3/20 0.44
TSHR P16473 3/20 0.44
RAB9A P51151 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
CYP3A4 P08684 2/20 0.44
TP53 P04637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19470796 0.91 RAPGEF4 (0.46) ALDH1A1TDP1POLBL3MBTL1NSD2
SCHEMBL19470800 0.89 RAPGEF4 (0.49) ALDH1A1TDP1POLBL3MBTL1NSD2
SCHEMBL19470808 0.88 ALDH1A1 (0.50) ALDH1A1TDP1POLBL3MBTL1NSD2
SCHEMBL9449481 0.86 ALDH1A1 (0.55) ALDH1A1TDP1POLBL3MBTL1NSD2
SCHEMBL11743126 0.85 ALDH1A1 (0.47) ALDH1A1TDP1POLBL3MBTL1NSD2
SCHEMBL9082450 0.85 RAPGEF4 (0.50) ALDH1A1TDP1POLBL3MBTL1NSD2
SCHEMBL7572634 0.84 ALDH1A1 (0.57) ALDH1A1TDP1POLBL3MBTL1NSD2
SCHEMBL30687380 0.84 NPC1 (0.46) ALDH1A1TDP1POLBNSD2PTGDR2
SCHEMBL8023017 0.84 NPC1 (0.46) ALDH1A1TDP1POLBNSD2PTGDR2
SCHEMBL31302025 0.83 ALDH1A1 (0.54) ALDH1A1TDP1POLBL3MBTL1NSD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8883715-B2 Biocompatible polymers, process for their preparation and compositions containing them BARRITAULT DENIS (FR) 2014-11-11 US disclosed
US-20130287725-A1 BIOCOMPATIBLE POLYMERS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM BARRITAULT DENIS (FR) 2013-10-31 US disclosed
US-8476220-B2 Biocompatible polymers, process for their preparation and compositions containing them BARRITAULT DENIS (FR) 2013-07-02 US disclosed
US-20110243881-A1 BIOCOMPATIBLE POLYMERS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM BARRITAULT DENIS 2011-10-06 US disclosed
US-7998922-B2 Process for treating fibroses with biocompatible polymer BARRITAULT DENIS 2011-08-16 US disclosed
US-20090012040-A1 BIOCOMPATIBLE POLYMERS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM BARRITAULT DENIS 2009-01-08 US disclosed
US-20040131583-A1 Therapy, medical diagnosis; cardiovascular disorders, central nervous system disorders, liver disorders, brain disorders; oxidation resistance BARRITAULT DENIS (FR) 2004-07-08 US disclosed
US-6689741-B2 DRUGS, MEDICAL DIAGNOSIS BARRITAULT DENIS (FR) 2004-02-10 US disclosed
US-20010021758-A1 Drugs, medical diagnosis BARRITAULT DENIS (FR) 2001-09-13 US disclosed
US-4891168-A Process for producing steroid derivatives NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1990-01-02 US disclosed
EP-0261656-A1 A process for producing steroid derivatives NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1988-03-30 EP disclosed