Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRR | Q9GZT4 | 2/20 | 0.62 |
| ▸ | PPARG | P37231 | 17/20 | 0.57 |
| ▸ | PPARA | Q07869 | 15/20 | 0.57 |
| ▸ | ACE | P12821 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24328238 | 1.00 | SRR (0.62) | SRRPPARGPPARAACE | |
| SCHEMBL5400441 | 0.87 | PPARA (0.71) | PPARGPPARA | |
| SCHEMBL5400438 | 0.87 | PPARA (0.71) | PPARGPPARA | |
| SCHEMBL7330792 | 0.86 | SRR (0.54) | SRRPPARGPPARA | |
| SCHEMBL7108081 | 0.86 | SLC7A5 (0.51) | SRRPPARGPPARA | |
| SCHEMBL5607289 | 0.86 | SLC7A5 (0.51) | SRRPPARGPPARA | |
| SCHEMBL7108323 | 0.86 | SLC7A5 (0.51) | SRRPPARGPPARA | |
| SCHEMBL14159050 | 0.86 | SRR (0.50) | SRRPPARGPPARA | |
| SCHEMBL24328386 | 0.84 | PPARG (0.58) | SRRPPARGPPARA | |
| SCHEMBL2866290 | 0.84 | GRIA2 (0.48) | SRRPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100522944-C | Carboxylic acid derivatives and salts thereof | EISAI CO LTD (JP) | 2009-08-05 | — | — | CN | disclosed |
| WO-2009061448-A2 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PROTEINURIC DISEASES | THE GENERAL HOSPITAL CORPORATION (US) | 2009-05-14 | — | — | WO | disclosed |
| CN-1503774-A | Carboxylic acid derivatives and salts thereof | ������������ʽ���� | 2004-06-09 | — | — | CN | disclosed |
| US-6028223-A | AN INTEGRIN ANTAGONISTS TREATING BONE DISORDER, PERIODONTAL DISEASE, OSTEOPOROSIS, HUMORAL HYPERCALCEMIA OF MALIGNANCY, PAGET'S DISEASE, TUMOR ANGIOGENESIS, DIABETIC RETINOPATHY, ARTHRITIS, SMOOTH MUSCLE CELL MIGRATION AND RESTENOSIS | G. D. SEARLE & CO. (US) | 2000-02-22 | — | — | US | disclosed |