SCHEMBL24328386

SCHEMBL24328386

CC(C)O[C@@H](Cc1ccc(F)cc1)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PPARG P37231 15/20 0.58
PPARA Q07869 15/20 0.58
PPARD Q03181 8/20 0.58
TRPA1 O75762 1/20 0.46
CPA1 P15085 1/20 0.45
SRR Q9GZT4 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7108323 0.85 SLC7A5 (0.51) PPARGPPARAPPARDSRR
SCHEMBL5607289 0.85 SLC7A5 (0.51) PPARGPPARAPPARDSRR
SCHEMBL7108081 0.85 SLC7A5 (0.51) PPARGPPARAPPARDSRR
SCHEMBL8023124 0.84 SRR (0.62) PPARGPPARASRR
SCHEMBL24328238 0.84 SRR (0.62) PPARGPPARASRR
SCHEMBL4335537 0.83 KMT2A (0.58) PPARGPPARAPPARD
SCHEMBL24328239 0.83 PPARG (0.59) PPARGPPARAPPARDCPA1SRR
SCHEMBL24328379 0.80 PPARA (0.66) PPARGPPARAPPARD
SCHEMBL13819362 0.80 MMP1 (0.55) PPARGPPARAPPARD
SCHEMBL4347157 0.80 PPARA (0.61) PPARGPPARAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230399297-A1 Novel Glutamine Analogs JACOBIO PHARMACEUTICALS CO., LTD (CN) 2023-12-14 US disclosed
US-20230399297-A1 Novel Glutamine Analogs JACOBIO PHARMACEUTICALS CO., LTD (CN) 2023-12-14 US disclosed
WO-2022078416-A1 NOVEL GLUTAMINE ANALOGS JACOBIO PHARMACEUTICALS CO., LTD. (CN) 2022-04-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230399297-A1 Novel Glutamine Analogs GLUL, GATD3, GLS PPARG 1211/4885PPARA 1857/4885PPARD 1270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.