Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 19/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8037470 | 0.85 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL8039330 | 0.80 | PTGS2 (0.68) | PTGS2PTGS1 | |
| SCHEMBL4032258 | 0.77 | GRIA2 (0.55) | PTGS2 | |
| SCHEMBL8023242 | 0.70 | PTGS2 (1.00) | PTGS2PTGS1PDPK1 | |
| SCHEMBL8033139 | 0.69 | PTGS2 (1.00) | PTGS2 | |
| SCHEMBL8032915 | 0.69 | PTGS2 (0.96) | PTGS2PTGS1PDPK1 | |
| SCHEMBL8023576 | 0.68 | PTGS2 (0.62) | PTGS2 | |
| SCHEMBL8023451 | 0.65 | PTGS2 (0.84) | PTGS2 | |
| SCHEMBL8032928 | 0.65 | PTGS2 (0.73) | PTGS2PTGS1 | |
| SCHEMBL8037662 | 0.65 | PTGS2 (0.73) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000066562-A1 | PYRAZOLES HAVING ANTIINFLAMMATORY ACTIVITY | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-11-09 | — | — | WO | claimed |
| WO-2000066562-A1 | PYRAZOLES HAVING ANTIINFLAMMATORY ACTIVITY | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-11-09 | — | — | WO | disclosed |