SCHEMBL8023262

SCHEMBL8023262

Cc1ccccc1OC(C)(O)Oc1ccccc1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
KDM4E B2RXH2 1/20 0.40
CYP1A2 P05177 1/20 0.40
ACHE P22303 1/20 0.39
ALDH1A1 P00352 2/20 0.37
GLA P06280 1/20 0.37
ALOX15 P16050 1/20 0.37
RXRA P19793 1/20 0.36
RXRB P28702 1/20 0.36
RXRG P48443 1/20 0.36
NOTUM Q6P988 1/20 0.36
AOC2 O75106 1/20 0.36
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36
SCN4A P35499 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6660490 0.86 TSHR (0.42) TSHRMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL31447203 0.86 TSHR (0.42) TSHRMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL13360664 0.83 TSHR (0.39) TSHRMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL29690513 0.81 TSHR (0.45) TSHRMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL2737142 0.81 TSHR (0.45) TSHRMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL28962643 0.78 TSHR (0.46) TSHRMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL28993162 0.78 NPC1 (0.36) TSHRMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL17365316 0.77 TSHR (0.42) TSHRMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL14547573 0.77 TSHR (0.42) TSHRMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL21497369 0.77 TSHR (0.42) TSHRMEN1KMT2ASMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2000212017-A DENTAL FILLER COMPOSITION OSAKA GAS CO LTD 2000-08-02 JP disclosed