SCHEMBL28993162

SCHEMBL28993162

Cc1ccccc1OC(C)(C)C(C)(C)O.OBO

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
TSHR P16473 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
KDM4E B2RXH2 1/20 0.35
CYP1A2 P05177 1/20 0.35
BCHE P06276 1/20 0.33
MAPT P10636 1/20 0.33
ALOX15 P16050 1/20 0.33
ALDH1A1 P00352 2/20 0.33
GLA P06280 1/20 0.33
ACHE P22303 1/20 0.32
RXRA P19793 1/20 0.32
RXRB P28702 1/20 0.32
RXRG P48443 1/20 0.32
NOTUM Q6P988 1/20 0.32
AOC2 O75106 1/20 0.32
MAOA P21397 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6660490 0.78 TSHR (0.42) NPC1RAB9ATSHRMEN1KMT2A
SCHEMBL8023262 0.78 TSHR (0.42) NPC1RAB9ATSHRMEN1KMT2A
SCHEMBL31447203 0.78 TSHR (0.42) NPC1RAB9ATSHRMEN1KMT2A
SCHEMBL28993193 0.77 HTR7 (0.41) RAB9ASMN1; SMN2KDM4EMAPTALDH1A1
SCHEMBL28640739 0.76 MAPT (0.44) SMN1; SMN2MAPTALDH1A1MAOALMNA
Boric Acid SCHEMBL29046186 0.75 TRPA1 (0.39) NPC1RAB9AMEN1KMT2AKDM4E
SCHEMBL28993181 0.75 CA4 (0.36) TSHRMEN1KMT2ACYP1A2MAPT
SCHEMBL13360664 0.75 TSHR (0.39) NPC1RAB9ATSHRMEN1KMT2A
SCHEMBL2737142 0.73 TSHR (0.45) NPC1RAB9ATSHRMEN1KMT2A
SCHEMBL29690513 0.73 TSHR (0.45) NPC1RAB9ATSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114874244-A Preparation method of arylboronic acid ester or alkyl boronate compound 中国科学院兰州化学物理研究所 2022-08-09 CN disclosed