SCHEMBL8023344

SCHEMBL8023344

CC1(C)C(=O)N(c2ccc(N)c(C(F)(F)F)c2)C(=O)N1Cc1ccc(Cl)nc1

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
IGF1R P08069 6/20 0.51
AR P10275 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8019157 0.89 AR (0.51) IGF1RAR
SCHEMBL2218361 0.87 AR (0.60) AR
SCHEMBL2216810 0.82 AR (0.50) IGF1RAR
SCHEMBL8014482 0.82 AR (0.52) IGF1RAR
SCHEMBL2216680 0.79 AR (0.65) IGF1RAR
SCHEMBL8021677 0.79 TAS2R8 (0.54) IGF1RAR
SCHEMBL1462547 0.79 AR (0.61) AR
SCHEMBL2219331 0.78 IGF1R (0.50) IGF1RAR
SCHEMBL8027038 0.77 AR (0.56) IGF1RAR
SCHEMBL634243 0.77 AR (0.64) AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009097995-A1 NOVEL PHENYL-SUBSTITUTED IMIDAZOLIDINES, METHOD FOR THE PRODUCTION THEREOF, MEDICAMENTS CONTAINING SAID COMPOUNDS AND USE THEREOF SANOFI-AVENTIS (FR) 2009-08-13 WO disclosed