SCHEMBL8019157

SCHEMBL8019157

CC1(C)C(=O)N(c2ccc(N)c(C(F)(F)F)c2)C(=O)N1Cc1ccc(C(F)(F)F)nc1

nearest known ligand 0.54

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AR P10275 3/20 0.51
IGF1R P08069 6/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2216680 0.90 AR (0.65) ARIGF1R
SCHEMBL8023344 0.89 IGF1R (0.51) ARIGF1R
SCHEMBL2216810 0.89 AR (0.50) ARIGF1R
SCHEMBL2214135 0.87 PGR (0.61) AR
SCHEMBL2219101 0.86 AR (0.53) ARIGF1R
SCHEMBL2219331 0.85 IGF1R (0.50) ARIGF1R
SCHEMBL8014482 0.81 AR (0.52) ARIGF1R
SCHEMBL8021677 0.80 TAS2R8 (0.54) ARIGF1R
SCHEMBL12438813 0.79 AR (0.49) ARIGF1R
SCHEMBL1461617 0.78 AR (0.62) AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009097995-A1 NOVEL PHENYL-SUBSTITUTED IMIDAZOLIDINES, METHOD FOR THE PRODUCTION THEREOF, MEDICAMENTS CONTAINING SAID COMPOUNDS AND USE THEREOF SANOFI-AVENTIS (FR) 2009-08-13 WO disclosed