Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21259673 | 1.00 | SLC6A4 (0.36) | SLC6A4MAPK3MAPK1TAS1R3TAS1R1 | |
| SCHEMBL23560939 | 1.00 | SLC6A4 (0.36) | SLC6A4MAPK3MAPK1TAS1R3TAS1R1 | |
| SCHEMBL21205425 | 1.00 | SLC6A4 (0.36) | SLC6A4MAPK3MAPK1TAS1R3TAS1R1 | |
| SCHEMBL23560936 | 0.90 | SLC6A4 (0.36) | SLC6A4MAPK3MAPK1TAS1R3TAS1R1 | |
| SCHEMBL16679944 | 0.87 | AURKA (0.40) | SLC6A4ADRB3AOC3CYP2B6ADRB2 | |
| SCHEMBL16679942 | 0.87 | AURKA (0.40) | SLC6A4ADRB3AOC3CYP2B6ADRB2 | |
| SCHEMBL21507534 | 0.86 | AKT1 (0.37) | SLC6A4ADRB3CYP2B6ADRB2ADRB1 | |
| SCHEMBL21507531 | 0.84 | ATM (0.36) | SLC6A4ADRB3AOC3CYP2B6ADRB2 | |
| SCHEMBL22467357 | 0.83 | ALDH1A1 (0.38) | SLC6A4KMT2ATAAR1SLC6A2SLC6A3 | |
| SCHEMBL22467355 | 0.83 | ALDH1A1 (0.38) | SLC6A4KMT2ATAAR1SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083526-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-09 | — | — | WO | disclosed |