SCHEMBL802374

SCHEMBL802374

Cc1cc(C)c(C)nn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24457880 0.73 ALDH1A1 (0.36)
Hydrochloric Acid SCHEMBL28814949 0.71 ALDH1A1 (0.35)
SCHEMBL13639089 0.71
SCHEMBL7754716 0.71
SCHEMBL1850181 0.71
SCHEMBL23091974 0.71
SCHEMBL20382913 0.71
SCHEMBL11985904 0.71
SCHEMBL22445417 0.71
SCHEMBL14008125 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230365558-A1 TETRAHYDROISOQUINOLINE DERIVATIVE AND USE THEREOF MEDSHINE DISCOVERY INC. (CN) 2023-11-16 US disclosed
US-20230365558-A1 TETRAHYDROISOQUINOLINE DERIVATIVE AND USE THEREOF MEDSHINE DISCOVERY INC. (CN) 2023-11-16 US disclosed
US-20230339902-A1 TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 C4 THERAPEUTICS, INC. (US) 2023-10-26 US disclosed
US-20230339902-A1 TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 C4 THERAPEUTICS, INC. (US) 2023-10-26 US disclosed
US-20230234945-A1 AZABICYCLYL-SUBSTITUTED HETEROCYCLES AS FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 2023-07-27 US disclosed
WO-2023139132-A1 FUNCTIONALIZED AMINOTHIAZOLES LEADXPRO AG (CH) 2023-07-27 WO disclosed
WO-2023102100-A1 ANTAGONISTS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 VANDERBILT UNIVERSITY (US) 2023-06-08 WO disclosed
WO-2023064343-A1 SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF VANQUA BIO, INC. (US) 2023-04-20 WO disclosed
WO-2023017263-A1 POTASSIUM CHANNEL MODULATORS AUTIFONY THERAPEUTICS LIMITED (GB) 2023-02-16 WO disclosed
WO-2022212819-A1 INDAZOLE DERIVATIVES AS ANTAGONISTS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 VANDERBILT UNIVERSITY (US) 2022-10-06 WO disclosed
US-20080118773-A1 Complex Composition, Polymer Complex Compound And Polymer Light-Emitting Device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-05-22 US disclosed
WO-2008048991-A2 ORGANIC COMPOUNDS NOVARTIS AG (CH) 2008-04-24 WO disclosed
US-20080003422-A1 Polymer Compound, Polymer Thin Film and Polymer Thin Film Device Using the Same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-01-03 US disclosed
US-20070270444-A1 Pyrazole compounds useful as protein kinase inhibitors VERTEX PHARMACEUTICALS INCORPORATED 2007-11-22 US disclosed
EP-1857521-A1 ORGANIC ELECTRIC FIELD LIGHT EMITTING ELEMENT AND PRODUCTION THEREFOR Mitsubishi Chemical Corporation (JP) 2007-11-21 EP disclosed
US-20070103059-A1 Composition and polymer light-emitting device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-05-10 US disclosed
US-20070040164-A1 Polymer complex compound and polymer light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-02-22 US disclosed
US-20070015757-A1 Novel Glucagon Antagonists/Inverse Agonists NOVO NORDISK A/S (DK) 2007-01-18 US disclosed
US-20070015757-A1 Novel Glucagon Antagonists/Inverse Agonists NOVO NORDISK A/S (DK) 2007-01-18 US disclosed
WO-2005058845-A2 NOVEL GLUCAGON ANTAGONISTS/INVERSE AGONISTS NOVO NORDISK A/S (DK) 2005-06-30 WO disclosed